Cancer Biology, Epidemiology, and Treatment in the 21st Century: Current Status and Future Challenges From a Biomedical Perspective
This article reviews the current status and future challenges of cancer biology, epidemiology, and treatment from a biomedical perspective, covering topics such as liquid biopsy, chemoprevention, immunoprevention, and new therapies.
Introduction to cancer and treatment approaches
Keywords. 1.1. Introduction. Cancer is the uninhibited growth and development of abnormal cells in the body, and is one of the foremost reasons of deaths throughout the world ( Paul and Jindal, 2017 ). These abnormal cells are commonly designated as cancerous cells, tumorous cells, or malignant cells. In 2018, cancer accounted for an estimated ...
Cancer: An unknown territory; rethinking before going ahead
Cancer is a disease of altered signaling and metabolism, causing uncontrolled division and survival of transformed cells. A host of molecules, factors, and conditions have been designated as underlying causes for the inception and progression of the disease. An enormous amount of data is available, system-wide interaction networks of the genes ...
New approaches and procedures for cancer treatment: Current
Introduction 7 8 9 In this narrative review, a general overview of the most advanced and novel cancer therapies was provided. In addition, also new strategies currently under investigation at the research stage that should overwhelm the drawbacks of standard therapies; different strategies to cancer diagnosis and therapy; and their current status in the clinical context, underlining their ...
Cancer
Cancer is characterized by proliferation of cells that have managed to evade central endogenous control mechanisms. Cancers are grouped according to their organ or tissue of origin, but increasingly also based on molecular characteristics of the respective cancer cells. Due to the rapid technological advances of the last years, it is now ...
Introduction to Cancer Biology
Introduction to Cancer Biology. Search within full text. Get access. Cited by 2. Robin Hesketh, University of Cambridge. Publisher: Cambridge University Press. Online publication date: February 2013.
Introduction As we have already seen, the mainstays of cancer therapy remain surgery and radiotherapy, both of which date from the 19th century but which have undergone a process of continual technical improvement, which is still ongoing. Drug treatments for cancer are comparatively much more recent. The first successful cancer drug therapy was the use of synthetic female hormones to treat ...
Review of cancer from perspective of molecular
In this study, we reviewed cancer from the perspective of the molecular level, in order to get a closer look at this disease. 2. Review method. Initially, we searched research papers using keywords such as cancer and molecular process, cancer and treatment and molecular aspects.
(PDF) cancer: an overview
PDF | Now a day's cancer is the most prevalent life threatening disease which is spreading because of the lifestyle we are living. Cancer is due to... | Find, read and cite all the research you ...
Breast cancer: introduction
Breast cancer is a life-threatening cancer and a leading cause of death among women. Breast cancer cases are increasing constantly due to the risk factors including age, menopause, obesity, use of hormone replacement therapy, family history, along with the environment and lifestyle factors. The increased awareness and newer diagnosis techniques ...
(PDF) CANCER CAUSES AND TREATMENTS
PDF | ABSTRACT: Cancer is a genetic disorder that results from genetic or epigenetic alterations in the somatic cells and has abnormal cell growth which... | Find, read and cite all the research ...
Introduction to Cancer
Cancer is a genetic disease. Yet, it is rarely the result of an inherited mutation that "runs" in a family. Instead, cancer generally arises from the accumulation of mutations in cells that cause ...
Cancer Cell Chemoresistance and Chemosensitization : Introduction and
INTRODUCTION Cancer, in general, is defined as a large group of diseases affecting any organ of the body. It constitutes the foremost causes of morbidity and mortality across the world, with an estimated 14.1 million new cases and approximately 8.2 million deaths in the year 2012. Notably, over the coming two decades, the number of cancer incidences is expected to rise by about 70% (WHO, 2017 ...
Introduction : The Cancer Journal
Author Information The Cancer Journal: 9/10 2019 - Volume 25 - Issue 5 - p 305-306 doi: 10.1097/PPO.0000000000000402 Buy Metrics
Understanding Cancer
In simple terms, cancer is a group of more than 100 diseases that develop across time and involve the uncontrolled division of the body's cells. Although cancer can develop in virtually any of the body's tissues, and each type of cancer has its unique features, the basic processes that produce cancer are quite similar in all forms of the disease.
Cancer: A Very Short Introduction
Abstract Cancer: A Very Short Introduction explains, in non-technical language, what cancer is and what it does. Why, despite constant improvements in treatment techniques, has cancer proved to be so hard to tackle? Why does cancer remain one of the largest causes of death worldwide? This VSI examines the different examples of cancer healthcare from around the world. It also investigates the ...
Explainable artificial intelligence in breast cancer detection and risk
Cancer Innovation is a high-quality, open access oncology journal publishing innovative papers on all aspects of basic and clinical cancer research.
An Introduction to Breast Cancer
Chapter 1: An Introduction to Breast Cancer 1.1 Introduction related to Cancer and its Treatment Methods There are many ter minologies regard ing cancer available in t he lite-
Cancer Research Paper
This research paper on global burden of cancer, its trends and projections, is split into four themes. The first section provides a basic description of the main sources of routine cancer information. The second section describes the international variation in cancer using the latest available cancer incidence, mortality, and prevalence estimates.
Why do patients with cancer die?
In this Roadmap, Boire et al. consider the immediate causes of mortality in patients with cancer, a topic not often considered in either preclinical or clinical research, and provide ...
Full article: Enhancing precision in colorectal cancer surgery
Research Paper. Enhancing precision in colorectal cancer surgery: development of an LGR5-targeting RSPO1 peptide mimetic as a contrast agent for intraoperative fluorescence molecular imaging ... Introduction. Colorectal cancer (CRC) is a common and lethal disease accounting for ~9% of all cancer deaths in the USA. Unfortunately, despite ...
Small molecule inhibitors of the VEGF and tyrosine kinase for the
This review paper highlights the genesis of cervical cancer and combating it using VEGF and tyrosine kinase inhibitors by delving into the details of the currently available inhibitors. Further, we have discussed the inhibitor molecules that are currently in various phases of clinical trials.
A review of cancer immunotherapy: from the past, to the present, to the
Abstract. Compared with previous standards of care (including chemotherapy, radiotherapy, and surgery), cancer immunotherapy has brought significant improvements for patients in terms of survival and quality of life. Immunotherapy has now firmly established itself as a novel pillar of cancer care, from the metastatic stage to the adjuvant and ...
Fluorine-18 Prostate-Specific Membrane Antigen-1007 PET/CT vs
Importance Prostate-specific membrane antigen (PSMA) demonstrates overexpression in prostate cancer and correlates with tumor aggressiveness. PSMA positron emission tomography (PET) is superior to conventional imaging for the metastatic staging of prostate cancer per current research but studies of second-generation PSMA PET radioligands for locoregional staging are limited.
Research To Practice
Introduction (0:00) Integration of Antibody-Drug Conjugates (ADCs) into the Care of Patients with Non-Small Cell Lung Cancer (NSCLC) and HER2 Alterations — Dr Paz-Ares (1:28) Emerging Role of TROP2-Targeted ADCs for NSCLC — Dr Sands (23:12) Other Promising Targets for ADCs for Lung Cancer — Dr Heist (39:07) CME information and select ...
Estimated effects of reductions in processed meat consumption and
Reductions in processed meat consumption could reduce the burden of some chronic diseases in the USA. However, more research is needed to increase certainty in the estimated effects of reducing unprocessed red meat consumption.
Breast Cancer—Epidemiology, Risk Factors, Classification, Prognostic
Breast cancer is the most common cancer among women. It is estimated that 2.3 million new cases of BC are diagnosed globally each year. Based on mRNA gene expression levels, BC can be divided into molecular subtypes that provide insights into new treatment ...
A new way to miniaturize cell production for cancer treatment
Researchers devised a way to miniaturize cell production for cancer treatment. The method for producing CAR-T cells, developed at the Singapore-MIT Alliance for Research and Technology, uses fewer resources and a smaller footprint than existing automated manufacturing platforms and could lead to more affordable methods of cell therapy manufacturing.
Staff Recognized for Outstanding Papers
Recipients of DCEG's Outstanding Paper Awards are recognized for outstanding research papers published in 2023. Winners demonstrate impact, innovation, and clarity of thought and language.
COMMENTS
This article reviews the current status and future challenges of cancer biology, epidemiology, and treatment from a biomedical perspective, covering topics such as liquid biopsy, chemoprevention, immunoprevention, and new therapies.
Keywords. 1.1. Introduction. Cancer is the uninhibited growth and development of abnormal cells in the body, and is one of the foremost reasons of deaths throughout the world ( Paul and Jindal, 2017 ). These abnormal cells are commonly designated as cancerous cells, tumorous cells, or malignant cells. In 2018, cancer accounted for an estimated ...
Cancer is a disease of altered signaling and metabolism, causing uncontrolled division and survival of transformed cells. A host of molecules, factors, and conditions have been designated as underlying causes for the inception and progression of the disease. An enormous amount of data is available, system-wide interaction networks of the genes ...
Introduction 7 8 9 In this narrative review, a general overview of the most advanced and novel cancer therapies was provided. In addition, also new strategies currently under investigation at the research stage that should overwhelm the drawbacks of standard therapies; different strategies to cancer diagnosis and therapy; and their current status in the clinical context, underlining their ...
Cancer is characterized by proliferation of cells that have managed to evade central endogenous control mechanisms. Cancers are grouped according to their organ or tissue of origin, but increasingly also based on molecular characteristics of the respective cancer cells. Due to the rapid technological advances of the last years, it is now ...
Introduction to Cancer Biology. Search within full text. Get access. Cited by 2. Robin Hesketh, University of Cambridge. Publisher: Cambridge University Press. Online publication date: February 2013.
VEGF and Notch signalling, 171-173 WNT and GPCR signalling, 164-165 cancer world patterns, 3-11 CancerBACUP, 17, 19 carcinogen, 28, 33, 42, 92, 230, 300, 310 glossary, 281 carcinoid, 256, 282, 288 carcinoma, 29, 35, 38, 75, 77, 88, 108, 120, 132, 147 glossary, 281 carcinosarcoma, glossary, 281 caretaker gene, glossary, 281 casein kinase ...
Introduction As we have already seen, the mainstays of cancer therapy remain surgery and radiotherapy, both of which date from the 19th century but which have undergone a process of continual technical improvement, which is still ongoing. Drug treatments for cancer are comparatively much more recent. The first successful cancer drug therapy was the use of synthetic female hormones to treat ...
In this study, we reviewed cancer from the perspective of the molecular level, in order to get a closer look at this disease. 2. Review method. Initially, we searched research papers using keywords such as cancer and molecular process, cancer and treatment and molecular aspects.
PDF | Now a day's cancer is the most prevalent life threatening disease which is spreading because of the lifestyle we are living. Cancer is due to... | Find, read and cite all the research you ...
Breast cancer is a life-threatening cancer and a leading cause of death among women. Breast cancer cases are increasing constantly due to the risk factors including age, menopause, obesity, use of hormone replacement therapy, family history, along with the environment and lifestyle factors. The increased awareness and newer diagnosis techniques ...
PDF | ABSTRACT: Cancer is a genetic disorder that results from genetic or epigenetic alterations in the somatic cells and has abnormal cell growth which... | Find, read and cite all the research ...
Cancer is a genetic disease. Yet, it is rarely the result of an inherited mutation that "runs" in a family. Instead, cancer generally arises from the accumulation of mutations in cells that cause ...
INTRODUCTION Cancer, in general, is defined as a large group of diseases affecting any organ of the body. It constitutes the foremost causes of morbidity and mortality across the world, with an estimated 14.1 million new cases and approximately 8.2 million deaths in the year 2012. Notably, over the coming two decades, the number of cancer incidences is expected to rise by about 70% (WHO, 2017 ...
Author Information The Cancer Journal: 9/10 2019 - Volume 25 - Issue 5 - p 305-306 doi: 10.1097/PPO.0000000000000402 Buy Metrics
In simple terms, cancer is a group of more than 100 diseases that develop across time and involve the uncontrolled division of the body's cells. Although cancer can develop in virtually any of the body's tissues, and each type of cancer has its unique features, the basic processes that produce cancer are quite similar in all forms of the disease.
Abstract Cancer: A Very Short Introduction explains, in non-technical language, what cancer is and what it does. Why, despite constant improvements in treatment techniques, has cancer proved to be so hard to tackle? Why does cancer remain one of the largest causes of death worldwide? This VSI examines the different examples of cancer healthcare from around the world. It also investigates the ...
Cancer Innovation is a high-quality, open access oncology journal publishing innovative papers on all aspects of basic and clinical cancer research.
Chapter 1: An Introduction to Breast Cancer 1.1 Introduction related to Cancer and its Treatment Methods There are many ter minologies regard ing cancer available in t he lite-
This research paper on global burden of cancer, its trends and projections, is split into four themes. The first section provides a basic description of the main sources of routine cancer information. The second section describes the international variation in cancer using the latest available cancer incidence, mortality, and prevalence estimates.
In this Roadmap, Boire et al. consider the immediate causes of mortality in patients with cancer, a topic not often considered in either preclinical or clinical research, and provide ...
Research Paper. Enhancing precision in colorectal cancer surgery: development of an LGR5-targeting RSPO1 peptide mimetic as a contrast agent for intraoperative fluorescence molecular imaging ... Introduction. Colorectal cancer (CRC) is a common and lethal disease accounting for ~9% of all cancer deaths in the USA. Unfortunately, despite ...
This review paper highlights the genesis of cervical cancer and combating it using VEGF and tyrosine kinase inhibitors by delving into the details of the currently available inhibitors. Further, we have discussed the inhibitor molecules that are currently in various phases of clinical trials.
Abstract. Compared with previous standards of care (including chemotherapy, radiotherapy, and surgery), cancer immunotherapy has brought significant improvements for patients in terms of survival and quality of life. Immunotherapy has now firmly established itself as a novel pillar of cancer care, from the metastatic stage to the adjuvant and ...
Importance Prostate-specific membrane antigen (PSMA) demonstrates overexpression in prostate cancer and correlates with tumor aggressiveness. PSMA positron emission tomography (PET) is superior to conventional imaging for the metastatic staging of prostate cancer per current research but studies of second-generation PSMA PET radioligands for locoregional staging are limited.
Introduction (0:00) Integration of Antibody-Drug Conjugates (ADCs) into the Care of Patients with Non-Small Cell Lung Cancer (NSCLC) and HER2 Alterations — Dr Paz-Ares (1:28) Emerging Role of TROP2-Targeted ADCs for NSCLC — Dr Sands (23:12) Other Promising Targets for ADCs for Lung Cancer — Dr Heist (39:07) CME information and select ...
Reductions in processed meat consumption could reduce the burden of some chronic diseases in the USA. However, more research is needed to increase certainty in the estimated effects of reducing unprocessed red meat consumption.
Breast cancer is the most common cancer among women. It is estimated that 2.3 million new cases of BC are diagnosed globally each year. Based on mRNA gene expression levels, BC can be divided into molecular subtypes that provide insights into new treatment ...
Researchers devised a way to miniaturize cell production for cancer treatment. The method for producing CAR-T cells, developed at the Singapore-MIT Alliance for Research and Technology, uses fewer resources and a smaller footprint than existing automated manufacturing platforms and could lead to more affordable methods of cell therapy manufacturing.
Recipients of DCEG's Outstanding Paper Awards are recognized for outstanding research papers published in 2023. Winners demonstrate impact, innovation, and clarity of thought and language.