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The power of peer editing: five questions to ask in the review.

research paper peer edit

You’ve put in the work of researching, reading, writing and revising your paper. You’ve read it out loud and followed the assignment requirements.

You’re going strong, but there’s still another step you need to perfect your paper.

The peer edit.

Utilizing peer review in your writing process may not always be easy. You’re offering the paper that you’ve spent hours on up for critique.

But the peer edit can be so beneficial in enhancing your writing.

We may often think of “peer review” in terms of journal articles that have been analyzed and approved for accuracy. While your paper won’t require that same heightened, professional level of critique, bringing it to one of your peers—whether a classmate, a friend, a mentor—can enhance your research paper greatly.

Here, we share about the importance of incorporating a peer review process for both the author and the reviewer.

What is Peer Review?

A peer review of your research paper is different than the editing process that you go through. Rather than you going through each section, citation, argument in your paper, someone else does. A peer review involves handing it to someone you trust to allow them to read it and provide feedback to help make your paper the best it can be.

This is no small feat. It requires you to be vulnerable about what you’ve written. You need to be willing to accept mistakes you may make and be committed to accepting their suggestions as a way to grow in your writing and academic work.

Why is Peer Review Important?

This stage of the editing process is unique in that pulls in another perspective. Unlike you, your peer editor hasn’t been immersed in reading and research on your paper’s topic. They don’t know for certain what direction your paper will go or what your arguments are.

This new, objective perspective brings great value in revision.

A fresh set of eyes sees issues, gaps, mistakes and clouded arguments that you may have missed or had not thought of.

When your peer editor sits down and sifts through your paper, they provide both positive comments of what’s going well in the paper, as well as opportunities for improvement in areas that may be unclear. Their input helps make your paper better, if you choose to follow their recommendations.

If you’re working with a classmate, trade papers and review each other’s paper. This not only allows you to receive feedback on your paper, but it also develops your skills in providing feedback and looking for specific elements in a paper. You become a better editor. Whether you’re passing your paper off or reviewing a paper, your skills in writing can be greatly enhanced.

Questions to Ask in the Peer Review

In the peer review process, it’s helpful to have a plan of action in addressing the paper. Below are five questions that can help guide the process. Whether you’re the author or the reviewer (or both), these five questions can help focus your attention on key components of the assignment and enhance your skills.

Question 1: Is the Audience and Purpose of the Paper Clearly Established?

As a reviewer, one of the first things you want to be sure to notice in the paper is if you can figure out who the paper is addressing. The audience of the paper should be evident in reference to the topic, the tone of the paper and the type of language used.

For example, if the paper contains a lot of jargon and industry-specific language, you could infer that the audience would be familiar with those terms. If not, you may want to suggest using less jargon or explaining the terms used.

The purpose of the paper should also be very clear and straightforward to you as the new reader. The thesis statement, most often in the introduction, should clearly convey the purpose. But from the opening to the main arguments to the concluding statement, the purpose of the paper should be obvious.

As a peer reviewer, you can help the author determine if both the audience and purpose of the paper are clearly established early on in the paper.

Question 2: Does the Main Point Match the Thesis Statement?

One of the most important sentences in the paper is the author’s thesis statement. The location and type of thesis statement depends on the kind of essay or paper. However, as a general rule, thesis statements should be concise, straightforward and clear in addressing the main argument.

As a new reader, you as the reviewer can provide great insight into the clarity of the thesis.

The Writing Center at the University of North Carolina has a helpful article on crafting the perfect thesis. In this article, they suggest you ask the following questions of the thesis statement:

  • Can I find the thesis statement?
  • Is the thesis specific enough?
  • Does the thesis answer the “so what” question of the paper?
  • Does the rest of the paper support the thesis statement?

Peer review can help enhance a thesis statement by noticing gaps or questions in the argument.

Question 3: Does the Paper Flow Well?

When you’re the writer of a paper, you may work in sections. First, you tackle main point A, then move onto B, add in C and finish up with a conclusion.

When you’re a peer reviewer, you’re reading it for the first time all in one glance. With this new perspective, you can more easily identify gaps, questions and concerns in the structure of the paper.

Does point A leap to point B leaving little to hold on to? Note that the author should include a better transition. Are you left wondering what point C has to do with point A? Highlight the need for a better connection between main points.

With an objective, outside perspective, you can help the author improve the flow and clarity of their paper to communicate most effectively.

Question 4: What Areas Need Additional Description?

As a reviewer of a paper, you want to fully understand the content you’re reading. And when you come across a section that you’re left wondering what’s going on, it can be frustrating.

An important question to ask as you review a paper is if each section contains sufficient description and detail to add value to the paper. Notice those areas that come across as too vague and uninteresting. Highlighting the desire for more information encourages the author to add clarity and enhance their ability to communicate effectively.

Question 5: Do you notice any grammar or word choice mistakes?

While this final question may be the most obvious, you want to help your author out by pointing out those grammar and word choice errors that she may have missed.

  • Is there an extra comma?
  • Does she have subject-verb agreement in all sentences?
  • Are most of the sentences in active voice?
  • Did they incorrectly cite their source?
  • Is there an extra tab in their reference page?

Being on the lookout for these types of errors can also help you as the reviewer to refresh your skills in grammar, punctuation, paragraphs and APA Style.

Incorporating a peer review process in finalizing a paper is immensely beneficial for both the author and the reviewer. Each elevates their writing skills. The author is more confident in the paper she submits and the reviewer grows in her editing ability.

Be Supported as You Pursue Your Goals

PGS offers numerous academic support resources to equip you to succeed in your degree program, whether that’s in writing a paper or other assignments. Visit our academic support web page to discover more essential tools.

Discover academic support

research paper peer edit

Ellie Walburg

Ellie Walburg (B.S.’17, M.B.A.’20) serves as the admissions communications coordinator for Cornerstone University’s Professional & Graduate Studies division.

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Online peer editing: effects of comments and edits on academic writing skills

a National Research University Higher School of Economics, Institute of Education, Myasnitskaya Ulitsa, 20, Moscow, 101000, Russia

Galina Shulgina

b EFL Department, Korea Advanced Institute of Science and Technology (KAIST), 291 Daehak-ro, Guseong-dong, Yuseong-gu, Daejeon, South Korea

Jamie Costley

Associated data.

The authors do not have permission to share data.

Although the effects of online peer editing have been studied from a number of perspectives, it remains unclear how giving and receiving comments and edits affect student academic writing performance. The current study examined the influence of these aspects of peer editing on student academic writing performance in higher education during online peer editing. Participants were 76 students engaged in peer editing of one another's work in a graduate scientific writing course at a Korean university. The relationships between the giving and receiving of comments and edits, and student performance on their writing tasks were analyzed. Results showed that there is a positive correlation between the number of comments received and the student's writing score, whereas receiving edits had the opposite effect and was associated with lower student performance. Furthermore, no relationship was found between giving comments or edits and writing performance. These results add to the field's understanding of how specific elements of peer editing can impact students' performance.

Academic writing; Comments; Edits; Online collaborative learning; Peer feedback.

1. Introduction

Due to the COVID-19 pandemic, blended and online learning have been used to provide students with diverse collaborative learning opportunities ( Al-Samarraie and Saeed, 2018 ; Zhu and Liu, 2020 ). Existing research recognizes that peer feedback is a valuable tool for improving student academic performance ( Al-Rahmi et al., 2015 ), thus interest has also grown in learner-to-learner interaction and how peer editing, as one type of collaboration, plays a role in interaction and student performance ( Zhou, 2017 ). Peer editing is defined as a collaborative learning process during which peers interact, review, critique, and edit each other's work ( Ebadi and Rahimi, 2017 ). It has been shown to be more effective than feedback from a teacher in some contexts ( Cho and MacArthur, 2011 ; Ciftci and Kocoglu, 2012 ; Nicol et al., 2014 ). In the context of academic writing, both providing and receiving feedback may help students improve their writing skills as this kind of peer interaction allows students to gain knowledge from different perspectives through social sharing ( Huisman et al., 2018 ). Furthermore, peer editing may lead both the giver and receiver of feedback to absorb information, and then decide how to judge the received messages through self-reflection ( Casey and Goodyear, 2015 ). Therefore, students may take some measures to narrow the gap and reach their potential after the feedback interpretation ( Carless and Boud, 2018 ; Wang et al., 2015 ; Zhu and Carless, 2018 ).

In online peer editing, providing comments or edits are the two most prevalent methods of providing feedback ( Magnifico et al., 2015 ). Comments refer to offering opinions and leaving suggestions, usually using the embed comments function in Microsoft word or another type of word processing software. On the other hand, providing edits means making direct changes to student original text, which generally shows up as a different color than what the original author wrote in ( Perron and Sellers, 2011 ). These two methods provide students an opportunity to discuss ideas and questions, review, criticize, and edit each other's work by adding suggestions and responding to them ( Lin and Reigeluth, 2016 ; Zhu and Carless, 2018 ), which activate key cognitive processes. Existing evidence supports the claim that peer feedback may improve students' academic writing performance ( Ebadi and Rahimi, 2017 ; Huisman et al., 2018 , 2019 ; Zhang et al., 2021 ). However, there is a lack of clarity regarding how giving and receiving comments and edits will affect students' writing performance separately, especially in an online collaborative context. This study intends to explore the impact of comments and edits on students' writing performance from both giving and receiving perspectives.

2. Literature review

2.1. two methods of online peer editing.

As an in-class collaborative activity, giving and receiving peer feedback through online peer editing has been shown to greatly benefit student writing ( Casey and Goodyear, 2015 ; Ebadi and Rahimi, 2017 ; Huisman et al., 2018 , 2019 ). The enhancement that peer editing brings to writers seems to be beyond an improvement in the quality of a particular piece of writing. Engaging in peer editing helps students develop greater self-assessment skills when compared with editing alone ( Nulty, 2011 ). It allows students to learn to critically review and revise their writing from the audience's perspective, thereby developing their independent thinking skills and self-directed learning ( Ebadi and Rahimi, 2017 ). Through communication and interaction with their peers, students become more actively engaged in their own writing ( Nicol and Macfarlane-Dick, 2006 ).

Online peer editing allows students to offer comments or edits to their peers. Specifically, comments refer to the leaving suggestions to identify the strengths and weaknesses of their peers, while edits are the act of inserting and/or deleting text written by other students ( Liu and Edwards, 2018 ). Once the editor has made the edits or left comments, the author of the text may respond to the comment, mark it as resolved, or delete it. In terms of edits of others, students can delete words and phrases directly, correct others’ spelling mistakes and add sentences or paragraphs. Compared to comments, edits provide direct changes without supporting arguments, which may, in some cases, prevent the author of the text from understanding the reasons for the proposed solution and, in turn, cause the author to decline it ( Liu and Edwards, 2018 ). Furthermore, the writer can often accept the changes without checking or understanding why the changes were made. Understanding the problem is an important predictor of effective feedback implementation ( Nelson and Schunn, 2009 ).

2.2. The influence of receiving comments on learning

Many studies have shown improvements in performance after students received comments during the learning process ( Huisman et al., 2018 , 2019 ; Zhang et al., 2021 ). A possible explanation is that receiving comments from others is helpful to student learning because during this process, receivers are encouraged to participate in the evaluation and reflection of their peers' comments ( Shvidko, 2015 ). Students may improve themselves as their peer has identified the pros and cons of their essays, and then the author may think about whether they agree with those opinions and find solutions to solve the problems noted by the reviewer ( Nicol et al., 2014 ).

However, it is not always the case that receiving comments will lead to improvements in writing or learning performance. For instance, some research has pointed out that receiving summaries, explanations, or ideas in comments is more helpful to student writing than some direct praise or criticism ( Wu and Schunn, 2020 ). Sometimes, students feel less motivated when they receive comments with no supporting evidence, which reduces the potential benefits of this type of peer activity ( Zhang and Hyland, 2018 ). Furthermore, comments may be ineffective if students do not consider, organize or fully implement them during the reflecting process ( Nicol and Macfarlane-Dick, 2006 ). Holmes and Papageorgiou (2009) suggested that if the comments students receive are of low quality or the allocation is not appropriate, they will not help students' writing. Thus, there is a lack of clarity on how different received comments affect students’ writing.

2.3. The influence of giving comments on learning

How giving comments might affect academic writing is another area of required investigation that is within the scope of peer feedback. There is some evidence that giving feedback may be even more important than receiving it ( Ion et al., 2019 ; Rouhi and Azizian, 2013 ). Students may develop their critical thinking abilities and metacognitive strategies through providing comments, and in some cases, their ability to problem-solve can be increased to a greater degree than those who receive feedback during the process of writing ( Cho and Cho, 2011 ; Frank et al., 2018 ). Through this process, students may explore ideas collaboratively and focus on the connections between ideas while seeking to improve their writing ( Neumann and McDonough, 2015 ).

During this process, students may produce, present, and develop their knowledge of a certain topic and share that knowledge with another learner whose work they are giving feedback on ( Tai et al., 2018 ). Furthermore, many studies have stated that generating explanations is an effective method to improve one's own writing ( Dunlosky et al., 2013 ; Nicol et al., 2014 ; Tempelaar et al., 2015 ). For instance, Cho and MacArthur (2010) pointed out that when students try to give an explanation by themselves, it is much more useful than receiving them from an expert. Those findings revealed that judging from a given text can enhance students' writing performance ( Henderson and Phillips, 2015 ).

However, effective feedback necessitates deliberate coordination between the provider and recipient in a peer feedback-friendly atmosphere ( Ray and Singh, 2018 ). In general, comments as a type of peer feedback should be provided only when the learner welcomes it ( Jug et al., 2019 ). In some cases, certain comments can incite social conflicts in groups so that some comments givers may try to offer praises or other kind suggestions to avoid conflicts within groups, which may not lead to the best learning outcomes ( Fong et al., 2018 ).

2.4. Receiving edits and student performance

Research has revealed that students can gain insights into their collaborators’ views on their work by reflecting on edits that others make of their work ( Mabbott and Bull, 2006 ). According to the quality of the edits and where they are directed, students can begin to understand the quality of their own work ( Hattie and Clarke, 2018 ). Furthermore, edits can range from simple superficial corrections, such as grammar or spelling errors, or more elaborate and deeper changes directed at the conceptual and knowledge level; after receiving and judging these edits, students may be more sensitive to avoid the same mistakes in their writing ( Petrović et al., 2017 ).

On the one hand, highlighting spelling or grammar mistakes helps to improve the quality of writing. On the other hand, getting only grammatical edits as feedback may make students question their peers' abilities and cause feelings of disappointment ( Birnholtz and Ibara, 2012 ; Liu and Edwards, 2018 ). In general, students believe that collaborative writing and peer editing lead to better quality work. However, while they may perceive their edits and suggestions as a source for improvement for others' texts, sometimes received edits may be seen as an intervention which makes their texts worse ( Blau and Caspi, 2009 ). Also, edits often only highlight mistakes, which makes students perceive them as direct criticism, which may be harmful for subsequent improvement of students' writing ( Tseng and Tsai, 2007 ), lower their sense of psychological ownership ( Blau and Caspi, 2009 ), or lead to conflict ( Birnholtz and Ibara, 2012 ). Interestingly, a high number of modifications may hurt students' feelings, while a small number of edits makes them feel uninvolved by their classmates. A lack of edits may be interpreted by students as an indication of disengagement or disinterest, which could negatively impact students’ writing ( Mabbott and Bull, 2006 ).

2.5. Giving edits and student performance

Many studies have confirmed the effectiveness of online editing among peers, such as edits of others, for improving their active learning, as discussed above regarding comments ( Wang, 2015 ). For instance, reading others' writing and correcting their errors can motivate them to seek information about what they are reading about or double-check their own understanding of concepts they are reviewing ( Wang, 2015 ; Yen et al., 2015 ).

However, several circumstances, such as a lack of expertise with peer editing in general and online learning in particular, may have a detrimental impact on the usefulness of edits in improving the student writing performance. According to Ishtaiwa and Aburezeq (2015) , opaque criteria for peer editing and the lack of information about the expected level of contribution may lead to minimal and/or overly formal student participation. Some students may also have difficulties with using some functions of the learning environment as a new instrument for learning, which can limit their participation ( Ishtaiwa and Aburezeq, 2015 ). Moreover, students often may try to avoid editing their peers’ work because of the risk of upsetting the author ( Birnholtz and Ibara, 2012 ; Coyle, 2007 ).

2.6. Present study

The present study seeks to explore the influence of giving and receiving peer feedback in the form of comments and edits on student learning. This study looks at the total amounts of comments and edits and does not investigate the quality or function of comments or edits. The reasons for this is that the first step in this type of research agenda is to look at the impact of the quantity of peer feedback elements on student writing performance. This gives a broad overview of how comments and/or edits impact student performance. This is a necessary first step in the understanding of how peer-to-peer feedback behaviors have on author and editor performance. Furthermore, when dealing with a high volume and number of students, as well as the use of technology for statistics and analysis, the amount of peer feedback is easier to obtain than the quality. This means that the outputs of comments and edits are readily available in the form of learning analytic visualizations more so than measures of edit or comment quality and function. Furthermore, this type of information can be more potential ready use for instructors to better understand online peer editing and implement instructional design choices that may help students improve their writing skills.

To achieve this, the present study collects data on comments and edits from peer editing sessions from 76 students over 5 cases of peer editing. Since most extant research explored the role of peer editing in broad ways such as surveys or interviews, the field has not yet dug deeply into how the volume of different peer editing methods influence students' learning performance. This study looks at peer editing by measuring comments and edits in students’ written documents directly in a collaborative learning context. To measure the performance of students, the overall individual writing scores are representative of the students' learning outcomes and performance during the course. The existing literature discussed above suggests that, on balance, giving and receiving comments and/or edits will lead to better learning performance and based on this, the present study has four main hypotheses:

Students who receive more comments will perform better in their writing.

Students who give more comments will perform better in their writing.

Students who receive more edits will perform better in their writing.

Students who give more edits will perform better in their writing.

3. Methodology

3.1. participants and learning context.

There were 76 students engaged in peer editing of each other's work in 4 sections of a graduate scientific writing course at a Korean university. Each of the 4 course sections had between 16 to 22 students. Among the subjects, 49 subjects were master's students, and 27 were in a doctoral program. There were 22 females and 54 males. The average age of the students was 25.7 (SD = 3.6), with a minimum age of 21 and a maximum age of 39 among the participants in the present study. The purpose of the scientific writing course was to teach students to write a journal manuscript on their graduate research findings ( Zhang et al., 2021 ). The course was given in an online format, and pre-recorded video lectures were provided on the course learning management system for students to view at their convenience. The course consists of 10 instructional weeks that respectively include 4 to 8 lecture videos, totaling 56 lecture videos for the course. The average length of a course video is nearly 12 min and covers topics related to scientific writing for graduate STEM students.

The ten instructional weeks of the course were grouped into two-week units designed to provide instruction related to the five major sections of a journal manuscript: 1) Introduction, 2) Methodology, 3) Results, 4) Discussion & Conclusion, and 5) Abstract. In the first week of a given unit, students would watch a set of videos specific to the journal section of interest for that unit. Videos in this first week explained the purpose, function, characteristics, and conventions of the given section of a journal manuscript. After viewing this initial set of videos, students would attend a live session of the course with the course instructor using Zoom teleconferencing software. After leading a short discussion on the topics of the course videos and answering any student questions, the instructor would put students into small groups for collaborative learning activities to reinforce their learning regarding the concepts covered in the lecture videos.

The second week of the unit consisted of another set of lecture videos often providing instruction on writing style, language, and grammar related to the same manuscript section focused on in the first week of the unit. Prior to the Zoom meeting of the second week of the unit, students were instructed to compose a first draft of a journal article section of focus in the unit and bring it to the meeting. While no special instructions were given to students in terms of word count, students were advised to consult journal style guides and published papers in their fields of study in deciding on the length and format of their written assignments. At the Zoom meeting, the instructor led a short discussion and answered questions and then provided instruction for the peer editing session. Then, students grouped themselves into dyads, and the instructor moved them into breakout rooms so that they could peer edit one another's writing. In the first week of the semester, students filled out a short questionnaire on their major, degree program, areas of research interest or expertise, and the title of their research project or paper. This information was shared with the class through a spreadsheet so that students could choose a peer editing partner with research interests that were as aligned as possible with their own. Ethical approval from a KAIST Institutional Review Board (IRB) named “The Effects of Collaborative Notetaking on Learning Outcomes in Online and Blended Learning Environments'' was received before conducting the questionnaire.

A Google Doc was created by the course instructor for each member of the dyad for each of five peer editing sessions, which corresponded to the Introduction, Methodology, Results, Discussion & Conclusion, and Abstract sections. Students were instructed to copy and paste their first draft of the journal manuscript section into the corresponding peer editing Google Doc and to share with and provide editing privileges to their dyad member. The peer editing Google Doc contained instructions for the students on how to peer edit their partner's work, and a video on how to peer edit an assignment was provided on the course learning management system. The instructions provided in the video and within each peer editing Google Doc required the students to track any changes to their partner's paper using “suggesting mode” rather than “editing mode”. This was done so that the original author of the work could easily see any changes that were made and would easily be able to accept or reject any changes according to preference. In addition, students were encouraged to make use of the embedded comment feature within the Google Docs platform, which allows a collaborator to highlight a given section of text and embed a comment that shows up in the right margin of the document. Replies to such comments are possible, so that the author and editor can engage in a comment thread if they desire. After providing such edits and comments, reviewers were asked to grade the quality of the draft using a specialized rubric provided by the course instructor adapted from Clabough and Clabough (2016) . The rubric assessed five criteria: four criteria specific to the content and function of a given section of a journal article and one general criterion related to the clarity and readability of the writing, and allowed students to rate the quality level of each criteria as “poor,” “average,” or “excellent”, giving scores of 0, 1, and 2, respectively. Accordingly, these subscores were added up and amounted to a final score from 0 to 10.

At the end of this second live Zoom meeting for a given unit, students were instructed to consider their partner's feedback on the first draft of their assignment and to create a final draft for submission on the course learning management system for final grading by the course instructor. Students were given two days to complete the revision, and the course instructor provided comments, suggestions, edits, and a final grade out of 10 points using the same specialized rubric that was used for peer editing. This 10-point grade accounted for 10% of the student's final grade in the course. Completion and grading of the final draft marked the end of a given unit, and the following week would begin a new unit of the course until all sections of the paper were completed.

3.2. Research instruments

Comments. Students can develop critical thinking skills, improve the structure of their writing, and gain new insights and perspectives when provided with written comments from their classmates ( Sung et al., 2016 ). In the present study, comments refer to written feedback students receive from a peer editing partner on their individual writing using embedded commenting features within the Google Docs platform. Such embedded comments appear as small frames in the margin of the document. Prior research has shown that embedded comments can be used to provide feedback and assessment at a variety of levels, from superficial, such as grammar and spelling, to highly complex, including deeper conceptualizations and connections of knowledge ( Luo et al., 2016 ; Strijbos and Wichmann, 2018 ; Sung et al., 2016 ). Embedded comments can also be used by editors and coauthors to ask questions and engage in online discussions in the margins of the document. For the purposes of this study, the number of embedded comments and replies to comments within a given peer editing Google Doc serves as the comments variable.

Edit of others. When peer editing one another's writing, students change or delete the writing of the original author of a text. In prior research, an increase in such edits of others was shown to correlate positively with students' ability to write clearly and to support their claims with evidence ( Yim et al., 2017 ). The edits of others variable i s the total number of characters inserted by a collaborator after the collaborator deleted text from the original author. This definition was originally provided by Wang et al. (2015) in their paper presenting DocuViz, an add-on for Google Chrome that enables collaborative data, including edits of others, to be mined and visualized from Google Docs. In the present research, DocuViz was used to mine this editing data from each of the peer editing Google Docs.

Writing assignments. The primary assignments for the scientific writing course examined in this study were the five major sections of a research manuscript: 1) Introduction, 2) Methodology, 3) Results, 4) Discussion & Conclusion, and 5) Abstract. Using a rubric adapted from Clabough and Clabough (2016) , these writing assignments were assessed by the course instructor and given a grade from 0 to 10. These assignment grades were then tallied to give a total writing score out of 50 points, accounting for 50% of the total grade points for the course.

Correlational analyses were conducted to examine the connection between the variables and then evaluated for significance to test the hypotheses. The first step of looking into the research questions was an overview of the main variables that were used as a part of this study. As can be seen in Table 1 , the authors wrote on average 2588 words, with the longest piece of work being 6829 words, and the shortest being 410 words. The students performed well in regards to their writing score, with the average score being 41 out of a possible 50. Also, worth noting is the lowest writing score attained in the sample population (32) is considered a passing grade for the writing portion of this class. The comments received and comments given have the same mean score of 11.16 embedded comments as these variables are the inverse of each other. As with comments, the edits received and edits given number of key-strokes have the same mean, which in the case of edits was 3881.38 keystrokes.

Table 1

Descriptive statistics for the main variables used in the study.

MinMaxMeanSDDescription
Author volume41068292587.681354.07Words
Writing score325041.363.96Rubric based score
Comments received04111.1610.93Embedded comments
Edits received10308183881.385539.64Keystrokes
Comments given04111.1611.16Embedded comments
Edits given0308183881.385539.64Keystrokes

To look more closely at the variables that could be analyzed as a part of this study, correlations between all main variables as well as author volume were calculated ( Table 2 ). The results show that receiving comments had a statistically significant positive association with writing score (.232∗). In contrast, receiving edits had a negative statistically significant association with writing score (-.325∗∗). In regards to the giving of comments and the giving of edits, neither variable had a statistically significant relationship with writing score.

Table 2

Correlations between all variables.

123456
1Author volume1
2Writing score.521∗∗1
3Comments received.466∗∗.232∗1
4Edits received.018-.325∗∗-0.191
5Comments given.162.087.485∗∗-.1171
6Edits given.270∗-.068-.118.327∗∗-.1811

∗∗Correlation is significant at the 0.01 level (2-tailed).

∗Correlation is significant at the 0.05 level (2-tailed).

Notable on this table are the positive associations between author volume and writing score (.521∗∗), comments received (.466∗∗) and edits given (.270∗). This shows that authors who produced more words had higher writing results. Furthermore, individuals who wrote more words encouraged their peers to comment on them more. Finally, people who wrote more appeared to be more likely to edit the work of others. Another finding that can be seen in this table is the positive relationship between giving comments and receiving comments (.485∗∗). Furthermore, there was also a positive relationship between receiving edits and giving edits (.327∗∗). These two results suggest that pairs tended to fall into a pattern of engaging in the same types of peer-editing - either commenting, or editing.

5. Discussion

Although previous research has investigated online peer editing, it remains unclear how the giving and receiving of comments and edits affect student writing performance. The current study explores the influence of these aspects on student academic writing performance in higher education by using Google Docs. The results show that receiving comments is positively associated with student writing performance. However, receiving edits has a negative association with student writing. In terms of giving comments and giving edits, neither technique has a statistically significant association with writing performance.

The findings indicate that students who receive more comments will write better papers, which coincides with evidence suggesting that students may improve their writing performance after receiving comments from their peers in the learning process ( Ebadi and Rahimi, 2017 ; Huisman et al., 2018 , 2019 ; Shvidko, 2015 ; Zhang et al., 2021 ). Students may improve their work based on the feedback they received, which identifies their writing's strengths and faults ( Casey and Goodyear, 2015 ). Students may identify answers to difficulties raised by the reviewer because of self-reflection, and their writing may improve as a result ( Nicol et al., 2014 ). This finding may be also due to the positive perceptions and attitudes of the learners because looking at others' comments through Google Docs provides learners with enough time and space to think, judge, and choose to accept or reject these suggestions, and eventually enhance their writing skills ( Ebadi and Rahimi, 2017 ). All students are masters and PhD in present study; thus, student writing may be in high quality and students may be more likely to receive higher quality comments from their high-performing peers. On the contrary, some research revealed that not all kinds of comments are effective ( Jug et al., 2019 ; Ray and Singh, 2018 ). One possible interpretation of this statement is that some comments are not well-structured or well-considered, so that students refuse to accept them. However, this research found that comments as suggestions and effective learning resources are useful to enhance student academic writing. As a result, comments should be expressed directly and clearly, and they should be comprehended independently of the giver; otherwise, receivers may not be able to grasp them, becoming confused and, in some cases, refusing to provide feedback ( Hattie and Clarke, 2018 ; Holmes and Papageorgiou, 2009 ).

Another finding of the present study is that giving comments during online peer editing has no association with students' writing performance. This contrasts with previous literature where giving comments to their peers can promote students' critical thinking and metacognitive strategies, thereby enabling improvement of their writing skills ( Cho and Cho, 2011 ; Frank et al., 2018 ; Dunlosky et al., 2013 ; Nicol et al., 2014 ). The finding in the present study may be related to the concerns of some feedback givers. For instance, students may try to avoid social conflicts within groups by only giving praise or soft advice to others, which may lead them to not engage personally with others’ work ( Fong et al., 2018 ; Robertson, 2011 ). Therefore, perhaps instructions are needed to guide students on how to deliver comments at deeper levels to improve writing before conducting online peer editing so that the givers of comments can also benefit from peer editing.

The most surprising result of the present study also shows that receiving edits negatively correlates with student writing performance, suggesting that such behaviors may stop students from improving their writing skills. This finding seems to contradict the work of Mabbott and Bull (2006) , who claimed that students will be more sensitive to their mistakes after reading and judging the edits from their peers, which should lead to better performance. However, the negative correlation between receiving edits and student writing is in line with Liu and Edwards (2018) , who illustrated that students may be upset or question the ability of their peers when they only received edits related to grammar or spelling errors. In turn, the effects of peer editing may rely on the quality of the reviewed writings ( Cho and Cho, 2011 ). When the editors look through a paper of poor quality, too many grammar and spelling errors make it difficult to give in-depth edits, thereby limiting the effects of edits on their peer's writing. For low-quality writing, it is possible that their peers are confused about the writing itself so that they are not able to offer edits. Interestingly, the average amount of edits received by students was 3881.38 characters. Receiving such large volumes of edits during collaborative learning may increase the workload of students' reflection, and students may only choose to accept all suggested edits without considering their accuracy, which may lead to a worse outcome in writing performance.

It is suggested by the results of the current study that giving more edits in groups does not drive better writing performance. It refutes the claim that reviewing others' sentences and pointing out their mistakes is a useful method to look for information and double check their own understanding of concepts mentioned by their peers ( Wang et al. 2015 ; Yen et al., 2015 ). This result likely has several causes. The first is that students may lack experience in using online collaborative technologies and giving edits online through Google Docs, which may hinder them from participating in online peer editing and gaining benefits from it ( Ishtaiwa and Aburezeq, 2015 ). Ludemann and McMakin (2014) found negative relationships between the first experience as a peer editor and assignment grades; however, for the second and subsequent sessions, this correlation did not hold. In the present study, five peer editing sessions were conducted. According to Jeffery et al. (2016) , the accuracy of peer editing is greatly impacted by the number of reviewers, and they suggested that there should be at least three reviewers for one academic paper. Therefore, interaction between two people may influence the results, especially if the feedback givers have little experience in peer editing. The second possible explanation for the negative association found in the present study is that students try to edit others’ sentences kindly and superficially to avoid upsetting the author ( Birnholtz and Ibara, 2012 ; Coyle, 2007 ). This type of editing may distract the author without any benefit as the edits are superficial and not helpful in increasing writing performance.

There are also some other interesting findings in the present study. For instance, positive correlations were found between author volume and their writing scores, comments received, and edits given. It is possible that when students have a well-rounded understanding of the topic, they may hold a positive attitude and prefer to express more in their writing. In turn, they will get higher scores than those who did not put a lot of effort into writing assignments. In addition, when the author volume becomes higher, there are more materials that can be provided to their peers for feedback, so that students may offer more comments and edits to their peers ( Nicol et al., 2014 ).

There is also a positive relationship between comments received and comments given, and between edits received and edits given. When considering the influence of peer review, one should remember that every student is both a reviewer and a writer ( Cho and Cho, 2011 ). Specifically, students act as reviewers to comment or edit on others' drafts, and as authors, they receive comments or edits from other reviewers’ perspectives ( Cho and Cho, 2011 ). Thus, the effect of receiving comments/edits and the role of giving comments/edits need to be considered together.

6. Conclusion

The aim of this research was to explore how giving and receiving comments and edits influence students' writing performance. Since previous studies used broad methods to investigate students' perspectives on peer editing, this paper fills a gap in the research on online peer feedback by categorizing feedback as comments or edits and separately examining them in documents. One of the contributions of the present study is that it reveals receiving comments during online peer editing is a useful method to improve student writing performance, which provides empirical evidence that judging and reflecting on received comments enables students to enhance their writing skills. Interestingly, another finding from this research showed that there is a negative correlation between receiving edits and students' writing performance, which may be due to the large volume of edits and the low level of students’ writing abilities. However, there is no statistically significant correlation between giving comments and/or edits and student writing performance. These findings suggest two important recommendations for instructors facilitating online peer editing sessions: 1) encourage students to participate in self-reflection after receiving comments actively and 2) provide some instructions before peer editing on how to give deeper levels of comments and edits during online peer editing. For example, before online collaboration, instructors can show students the example of good peer feedback and point out what types of feedback can enhance their writing.

Since online learning has become increasingly popular, the present research is particularly relevant as it suggests new avenues for improving students' online writing performance in online settings. However, there are some limitations to this research. For instance, in this study, students could choose their own partners rather than having partners randomly assigned to conduct online peer editing. In this case, students may prefer to give kind suggestions or less edits to protect their friends' feelings, which may have a negative influence on the outcome of this research. Thus, future research should assign students to different groups randomly to increase the validity of research. Another limitation is that while this study accounts for edits and comments that were provided by peers within a Google Doc, it does not account for backchannel communication occurring outside the document, including discussions during Zoom video conferencing while the peers edited each other's’ work or subsequent communications proceeded via email or text messaging. While such backchannel communications would likely provide a rich source of data on students' collaborative processes, the collection of such information would be invasive to students' privacy and is not allowed by the institutional review board that granted permission for the present study. One other limitation is that the present study only took into account the number of comments and modifications, not their intention or quality. More extensive research in the future might take into account both the quantity and quality of comments and edits. More study could be done to develop a systematic method for accounting for these two factors. Although previous research has investigated the influence of peer editing on student academic writing, further exploration is needed on how giving and receiving peer feedback online affect students' writing. Since comments and edits, two popular modes of online editing, play an essential role in cooperative learning, more research is needed to explore the impact of peer editing in online contexts.

Declarations

Author contribution statement.

Han Zhang: Conceived and designed the experiments; Wrote the paper.

Galina Shulgina: Contributed reagents, materials, analysis tools or data; Wrote the paper.

Mik Fanguy: Performed the experiments.

Jamie Costley: Analyzed and interpreted the data.

Funding statement

This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

Data availability statement

Declaration of interests statement.

The authors declare no conflict of interest.

Additional information

This article is an output of a research project implemented as part of the Basic Research Program at the National Research University Higher School of Economics (HSE University). Supplementary content related to this article has been published online at doi: https://doi.org/10.1016/j.heliyon.2022.e09822 .

Appendix A. Supplementary data

The following is the supplementary data related to this article:

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Editing Research

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The Truth about Peer Editing

Featured Image

Peer editing is a common part of the curriculum for writing students, but does it actually teach the students anything? Studies say yes.

If you’ve taken a writing class, especially at the university level, you’re probably familiar with the concept of peer editing. You and a classmate swap pieces and edit one another’s work. Peer editing happens all the time, but does it actually help? Does peer editing improve students’ writing skills? Does it boost their editing skills? According to Jessica Holt , a professor at the University of Georgia, the answer seems to be yes.

THE RESEARCH 

In Holt’s article “ Grade-Accountable Peer Editing: Students’ Perceptions of Peer-Editing Assignments ,” she describes research on how university-level communications students perceive the peer-editing process. In the study, students in two communications classes were given several peer-editing assignments throughout the semester. 

At the conclusion of the semester, the students participated in focus groups to discuss their perceptions about the peer-editing process. Holt discovered that the students overwhelmingly perceived peer editing to be helpful but unpleasant and that many students didn’t believe peer-editing skills would be relevant after entering the workforce. One student stated, “I think that peer editing can be good, but in all honesty, I would rather have a teacher edit my paper or like my boss or whoever the end-all, be-all person is.”

“Peer review has been shown to promote the recognition of good practice as well as critical and constructive collaborative dialogue.” —Jennifer brill and charles hodges (2011)

THE IMPLICATIONS

Though university students in writing-heavy disciplines may believe that peer reviewing is just a classroom tactic, peer review can be much more than that. Holt’s and others’ research shows that learning to effectively edit peers’ work can help individuals improve their ability to edit, including in the workplace. For example, Jennifer Brill and Charles Hodges noted in the article “ Investigating Peer Review as an Intentional Learning Strategy to Foster Collaborative Knowledge-Building in Students of Instructional Design ” that “peer review has been shown to promote the recognition of good practice as well as critical and constructive collaborative dialogue.” Peer review is also a great way to sharpen writing and communication skills. Giving feedback and receiving feedback are skills that all writers and editors can benefit from and, like other skills, require practice to develop. One way to practice is through peer review.

To learn more about the benefits of peer editing, read the full article:

Holt, Jessica. (2019). “Grade-Accountable Peer Editing: Students’ Perceptions of Peer-Editing Assignments.” Journalism & Mass Communication Educator 74 (1): 31–43. https://doi.org/10.1177/1077695818764959 .

—Erin Johnston, Editing Research

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Find more research

Read Pantelis Papadopoulos, Thomas Lagkas, and Stavros Demitriadis’s (2012) article on different methods to make peer reviewing as effective as possible: “How to Improve the Peer Review Method: Free-Selection vs. Assigned-Pair Protocol Evaluated in a Computer Networking Course.” Computers & Education 59  (2): 182–95. https://doi.org/10.1016/j.compedu.2012.01.005 . 

Check out Lloyd Rieber’s article on how peer editing can help students in business disciplines: Rieber, Lloyd J. (2012). “Using Peer Review to Improve Student Writing in Business Courses.” Journal of Education for Business 81 (6): 322–26. https://doi.org/10.3200/JOEB.81.6.322-326 .

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Erin Johnston

Had so much fun doing this research.

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As someone who hasn’t always enjoyed the peer-editing process, I liked being able to see how it would be relevant to life outside of the classroom. Writing doesn’t end when we graduate, so it makes sense that peer editing wouldn’t end either.

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I definitely agree! We can all benefit from each other’s perspectives, no matter how experienced we are.

Peer Editing to the Rescue! - Editing Research

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Peer editing

Peer editing can be done during class time or electronically outside of class, as the documents below--from Northwestern instructors--illustrate.  The questions that students respond to can vary according to the nature of the assignment and the purpose of the peer review.

peer editing sheets for drafts Peer editing sheets for two essay assignments in a freshman seminar.  Providing very specific questions helps the editors give useful feedback and suggestions. 

peer feedback form literature seminar Students exchange drafts in class, complete the peer feedback form, and then discuss their written comments with one another.  Students submit the forms with their drafts so that I can read them.  I frequently refer to their peers' comments when I am writing my own comments on their drafts.   

peer review Asian diaspora freshman seminar Students do a close reading of one another's drafts to provide insight into what has and has not been conveyed by the draft.

research draft peer review Prompts peer reviewers to comment on key pieces of information, logical organization, and conclusion

research paper introduction peer response Prompts peer editor to comment on introduction, and prompts author to respond to those comments

research paper peer evaluation of claims Prompts peer editor to evaluate the paper's effectiveness in supporting claims and addressing counter-arguments

peer editing science papers Prompts peer editor to complete a checklist on the paper's content, structure, and grammar

getting the most out of peer reviews A link to NU's Writing Place that explains how to make sure you benefit from sharing your writing with peers

peer review guidelines for a personal essay These guidelines from a freshman seminar are aimed at pairs of students who are exchanging drafts before meeting individually with the instructor. 

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Lend Me Your Peers: How to Make the Most of Peer Editing Sessions

September 1, 2017

By Andrew Koch, Writing Tutor

"And be sure to bring a draft of your paper for next week's class. We're having a peer review day."

(Internal groan)

Peer editing days are like Cincinnati weather: either great or miserable, with not much in between. The right suggestions from classmates about your writing can give you great insights on how to improve your paper, but if you're anything like me, you find bad peer editing can be a real drag.

Bad peer editing comes in many forms, from the hypercritical (red ink dripping from every line) to the unresponsive (a blank expression and a shrug when you ask "So what'd you think?"), and the worst peer editing can make you feel worse about your paper than when you began the session. Many professors have students critique others' works as a way of improving writing, but misguided peer review sessions can turn into time spent either politely nodding and discussing weekend plans and last night's game or (worse) passive-aggressively tearing each other's papers apart. Sometimes a student may not know what kind of advice to give to a classmate, especially if he or she is personally struggling to understand the assignment.

But you don't have to settle for anything less than the best from these sessions! As is the case in many areas in life, you'll get what you give from peer editing. By committing to being a better peer editor, you're helping to improve the peer editing culture and showing your classmate what kind of feedback you're looking for in return. By learning the right questions to ask, your partner and you can both walk away with a better paper and more confidence about the assignment. Here are some ways to help you get the most out of peer editing sessions:

Look at the big picture. A common mistake among editors is putting too much focus on "proofreading" and not enough on the content of a paper. Though it pains me (a grammar nerd) to admit it, good peer editing is about a lot more than policing spelling and punctuation. Rather, good peer editing ensures that a piece of writing, in addition to being grammatically correct, makes sense to the audience and is accomplishing what the assignment asks. Don't be afraid to ask more general questions about the paper and its structure and focus. Is the writer's focus too broad? Too specific? In an argumentative paper, is the writer's main opinion coming through? Are there ways that the writer could be clearer? Does your partner's paper fulfill the assignment's requirements in terms of focus?

Listen to the writer and let him/her guide. See if there's a specific aspect of the paper that your partner is concerned about. While some of your fellow students might not know what they want to improve about their writing/assignment, others will more precisely know how they want to better develop the paper. As a peer editor, your goal is to help the other student improve his or her assignment and writing ability, whatever shape that may take, and your classmate will do the same for you. As tempting as it might seem, this is not a chance for you to show off your intelligence or writing prowess. Remember to stay focused on what your review session partner needs and follow his or her lead.

Read the paper out loud. If you've been to the Writing Center, you're probably familiar with this technique, one of our favorites. It's easy to become bogged down in your own words while writing a piece, but verbally revisiting your words by doing a read through can help you catch content weaknesses and, yes, spelling and grammar mistakes, too, by revisiting your language in a new way. Time permitting, have your partner read his or her paper aloud to you.

Ask questions and be patient. If you're unsure about something in your partner's paper, just ask! Writers love to talk about their writing, and face-to-face communication allows you the opportunity to quickly and efficiently ask questions and get feedback. Don't assume that you understand what a writer is saying - feel free to pick your partner's brain about his or her subject or topic. I've often found that my best ideas come when I'm explaining my paper's subject or my writing assignment to someone else.

Being a better peer editor for someone else can help you focus on your own writing as well. By being a more thoughtful peer editor, you can break the cycle of unproductive and unhelpful peer editing sessions, and everybody will win.

research paper peer edit

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How to Write and Publish a Research Paper for a Peer-Reviewed Journal

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  • Published: 30 April 2020
  • Volume 36 , pages 909–913, ( 2021 )

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  • Clara Busse   ORCID: orcid.org/0000-0002-0178-1000 1 &
  • Ella August   ORCID: orcid.org/0000-0001-5151-1036 1 , 2  

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Communicating research findings is an essential step in the research process. Often, peer-reviewed journals are the forum for such communication, yet many researchers are never taught how to write a publishable scientific paper. In this article, we explain the basic structure of a scientific paper and describe the information that should be included in each section. We also identify common pitfalls for each section and recommend strategies to avoid them. Further, we give advice about target journal selection and authorship. In the online resource 1 , we provide an example of a high-quality scientific paper, with annotations identifying the elements we describe in this article.

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How to Choose the Right Journal

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The Point Is…to Publish?

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Writing and publishing a scientific paper

Avoid common mistakes on your manuscript.

Introduction

Writing a scientific paper is an important component of the research process, yet researchers often receive little formal training in scientific writing. This is especially true in low-resource settings. In this article, we explain why choosing a target journal is important, give advice about authorship, provide a basic structure for writing each section of a scientific paper, and describe common pitfalls and recommendations for each section. In the online resource 1 , we also include an annotated journal article that identifies the key elements and writing approaches that we detail here. Before you begin your research, make sure you have ethical clearance from all relevant ethical review boards.

Select a Target Journal Early in the Writing Process

We recommend that you select a “target journal” early in the writing process; a “target journal” is the journal to which you plan to submit your paper. Each journal has a set of core readers and you should tailor your writing to this readership. For example, if you plan to submit a manuscript about vaping during pregnancy to a pregnancy-focused journal, you will need to explain what vaping is because readers of this journal may not have a background in this topic. However, if you were to submit that same article to a tobacco journal, you would not need to provide as much background information about vaping.

Information about a journal’s core readership can be found on its website, usually in a section called “About this journal” or something similar. For example, the Journal of Cancer Education presents such information on the “Aims and Scope” page of its website, which can be found here: https://www.springer.com/journal/13187/aims-and-scope .

Peer reviewer guidelines from your target journal are an additional resource that can help you tailor your writing to the journal and provide additional advice about crafting an effective article [ 1 ]. These are not always available, but it is worth a quick web search to find out.

Identify Author Roles Early in the Process

Early in the writing process, identify authors, determine the order of authors, and discuss the responsibilities of each author. Standard author responsibilities have been identified by The International Committee of Medical Journal Editors (ICMJE) [ 2 ]. To set clear expectations about each team member’s responsibilities and prevent errors in communication, we also suggest outlining more detailed roles, such as who will draft each section of the manuscript, write the abstract, submit the paper electronically, serve as corresponding author, and write the cover letter. It is best to formalize this agreement in writing after discussing it, circulating the document to the author team for approval. We suggest creating a title page on which all authors are listed in the agreed-upon order. It may be necessary to adjust authorship roles and order during the development of the paper. If a new author order is agreed upon, be sure to update the title page in the manuscript draft.

In the case where multiple papers will result from a single study, authors should discuss who will author each paper. Additionally, authors should agree on a deadline for each paper and the lead author should take responsibility for producing an initial draft by this deadline.

Structure of the Introduction Section

The introduction section should be approximately three to five paragraphs in length. Look at examples from your target journal to decide the appropriate length. This section should include the elements shown in Fig.  1 . Begin with a general context, narrowing to the specific focus of the paper. Include five main elements: why your research is important, what is already known about the topic, the “gap” or what is not yet known about the topic, why it is important to learn the new information that your research adds, and the specific research aim(s) that your paper addresses. Your research aim should address the gap you identified. Be sure to add enough background information to enable readers to understand your study. Table 1 provides common introduction section pitfalls and recommendations for addressing them.

figure 1

The main elements of the introduction section of an original research article. Often, the elements overlap

Methods Section

The purpose of the methods section is twofold: to explain how the study was done in enough detail to enable its replication and to provide enough contextual detail to enable readers to understand and interpret the results. In general, the essential elements of a methods section are the following: a description of the setting and participants, the study design and timing, the recruitment and sampling, the data collection process, the dataset, the dependent and independent variables, the covariates, the analytic approach for each research objective, and the ethical approval. The hallmark of an exemplary methods section is the justification of why each method was used. Table 2 provides common methods section pitfalls and recommendations for addressing them.

Results Section

The focus of the results section should be associations, or lack thereof, rather than statistical tests. Two considerations should guide your writing here. First, the results should present answers to each part of the research aim. Second, return to the methods section to ensure that the analysis and variables for each result have been explained.

Begin the results section by describing the number of participants in the final sample and details such as the number who were approached to participate, the proportion who were eligible and who enrolled, and the number of participants who dropped out. The next part of the results should describe the participant characteristics. After that, you may organize your results by the aim or by putting the most exciting results first. Do not forget to report your non-significant associations. These are still findings.

Tables and figures capture the reader’s attention and efficiently communicate your main findings [ 3 ]. Each table and figure should have a clear message and should complement, rather than repeat, the text. Tables and figures should communicate all salient details necessary for a reader to understand the findings without consulting the text. Include information on comparisons and tests, as well as information about the sample and timing of the study in the title, legend, or in a footnote. Note that figures are often more visually interesting than tables, so if it is feasible to make a figure, make a figure. To avoid confusing the reader, either avoid abbreviations in tables and figures, or define them in a footnote. Note that there should not be citations in the results section and you should not interpret results here. Table 3 provides common results section pitfalls and recommendations for addressing them.

Discussion Section

Opposite the introduction section, the discussion should take the form of a right-side-up triangle beginning with interpretation of your results and moving to general implications (Fig.  2 ). This section typically begins with a restatement of the main findings, which can usually be accomplished with a few carefully-crafted sentences.

figure 2

Major elements of the discussion section of an original research article. Often, the elements overlap

Next, interpret the meaning or explain the significance of your results, lifting the reader’s gaze from the study’s specific findings to more general applications. Then, compare these study findings with other research. Are these findings in agreement or disagreement with those from other studies? Does this study impart additional nuance to well-accepted theories? Situate your findings within the broader context of scientific literature, then explain the pathways or mechanisms that might give rise to, or explain, the results.

Journals vary in their approach to strengths and limitations sections: some are embedded paragraphs within the discussion section, while some mandate separate section headings. Keep in mind that every study has strengths and limitations. Candidly reporting yours helps readers to correctly interpret your research findings.

The next element of the discussion is a summary of the potential impacts and applications of the research. Should these results be used to optimally design an intervention? Does the work have implications for clinical protocols or public policy? These considerations will help the reader to further grasp the possible impacts of the presented work.

Finally, the discussion should conclude with specific suggestions for future work. Here, you have an opportunity to illuminate specific gaps in the literature that compel further study. Avoid the phrase “future research is necessary” because the recommendation is too general to be helpful to readers. Instead, provide substantive and specific recommendations for future studies. Table 4 provides common discussion section pitfalls and recommendations for addressing them.

Follow the Journal’s Author Guidelines

After you select a target journal, identify the journal’s author guidelines to guide the formatting of your manuscript and references. Author guidelines will often (but not always) include instructions for titles, cover letters, and other components of a manuscript submission. Read the guidelines carefully. If you do not follow the guidelines, your article will be sent back to you.

Finally, do not submit your paper to more than one journal at a time. Even if this is not explicitly stated in the author guidelines of your target journal, it is considered inappropriate and unprofessional.

Your title should invite readers to continue reading beyond the first page [ 4 , 5 ]. It should be informative and interesting. Consider describing the independent and dependent variables, the population and setting, the study design, the timing, and even the main result in your title. Because the focus of the paper can change as you write and revise, we recommend you wait until you have finished writing your paper before composing the title.

Be sure that the title is useful for potential readers searching for your topic. The keywords you select should complement those in your title to maximize the likelihood that a researcher will find your paper through a database search. Avoid using abbreviations in your title unless they are very well known, such as SNP, because it is more likely that someone will use a complete word rather than an abbreviation as a search term to help readers find your paper.

After you have written a complete draft, use the checklist (Fig. 3 ) below to guide your revisions and editing. Additional resources are available on writing the abstract and citing references [ 5 ]. When you feel that your work is ready, ask a trusted colleague or two to read the work and provide informal feedback. The box below provides a checklist that summarizes the key points offered in this article.

figure 3

Checklist for manuscript quality

Data Availability

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Vetto JT (2014) Short and sweet: a short course on concise medical writing. J Cancer Educ 29(1):194–195

Brett M, Kording K (2017) Ten simple rules for structuring papers. PLoS ComputBiol. https://doi.org/10.1371/journal.pcbi.1005619

Lang TA (2017) Writing a better research article. J Public Health Emerg. https://doi.org/10.21037/jphe.2017.11.06

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Acknowledgments

Ella August is grateful to the Sustainable Sciences Institute for mentoring her in training researchers on writing and publishing their research.

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Busse, C., August, E. How to Write and Publish a Research Paper for a Peer-Reviewed Journal. J Canc Educ 36 , 909–913 (2021). https://doi.org/10.1007/s13187-020-01751-z

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Peer review checklists

Use this guide to write your reviewer report.

The checklists below are intended to help maximize your time, by being a useful guide while you carry out your peer review task.

When you use a peer review checklist, it will be easier to rate each of the parts in the paper you’re reviewing according to their strength. This will also make sure you don’t miss any critical steps in the process. 

Peer review expectations and requirements will vary between different subject areas and article types, which is why we’ve prepared a number of different checklists to guide you through the process. First, read our guide to writing your review report then, choose the most appropriate checklist for the work you’ve been asked to review.

Are you peer reviewing a PLS or PLSP? These guides might be useful too:

Plain Language Summary peer review guidelines

Plain Language Summary of Publication peer review guidelines

Before you begin

Have you read the general guidelines for peer reviewers ?

Do you understand the peer review process of the journal you’re reviewing for?

Do you know the journal’s aims and scope? 

Are you familiar with the journal’s instructions for authors?

If you are confident with your answers to the above questions, please read our step-by-step guide to writing your reviewer report. Then choose the checklist that is most suitable for the manuscript you’re reviewing. 

How to write a peer review report

Below is a step-by-step guide to help you review a manuscript and make your recommendation.

Research the journal

Visit the journal homepage on  Taylor & Francis Online and read the aims and scope and instructions for authors to get a sense of the journal’s scope and content. This will help you determine if the paper you’re reviewing is suitable for the journal or not.

Read the paper

While you read the paper remember to check over any tables, figures, or supplementary data. Bear in mind that the main factors you should provide advice on are:

The originality, presentation, and relevance of the manuscript’s subject matter to the readership of the journal.

The accuracy and validity of the methodology, and whether the conclusions are appropriately supported.

Write your report

There are two purposes for your report: to provide the editor with information to enable them to make a decision, and to provide feedback to the author to help improve their work.

It is often helpful to begin with a brief summary of the work and the main findings as you understand them, along with a summary of your overall opinion.

Being critical whilst remaining sensitive to the author isn’t always easy. A good rule is to direct your criticism towards the work carried out and avoid comments that may be interpreted as personal criticism of the author.

Here are a few things to consider when writing your report:

Your comments must be suitable to send to the author. Please make constructive suggestions, seek clarification on any unclear points, and ask for further elaboration. Remember that authors will welcome positive feedback as well as constructive criticism.

If the paper reports original research, comment on whether the methods are appropriate and whether the work was carried out to the standards expected within your field.

Note any aspects that you are unable to assess, whether this is due to lack of clarity or because it is outside your expertise.

You should make suggestions on how the author can improve clarity, conciseness, and the quality of the presentation.

Confirm whether you feel the subject of the paper is sufficiently interesting to justify its length. If you recommend shortening, mention specific areas where you think this is required.

It’s not the reviewer’s job to edit the paper for spelling, grammar, etc., but it is helpful if you can note specific points where the technical meaning is unclear.

You may disagree with the author’s opinions, but you should allow them to argue their case, provided their evidence supports it.

Reviewers are not expected to detect research integrity concerns in manuscripts, but your expertise may allow you to spot potential issues that editorial staff or the editor have missed. If you suspect misconduct, please let the publisher or the editor know as soon as possible.

Please consult the reviewer checklists below (where applicable) while reading the paper and writing your report:

Science, Technology, Engineering and Mathematics (STEM) research article checklist

Arts and humanities research article reviewer checklist

Clinical research article reviewer checklist

Non-research article reviewer checklist

Provide detailed feedback

Comments should be carefully worded so the author understands what actions they need to take to improve their paper, rather than just stating what is wrong.

Try to write simply and avoid rhetorical flourishes that may lead to misunderstandings. Also, avoid generalized or vague statements as well as negative comments which aren’t relevant or constructive.

Example of peer review comments

Please note that these are just examples of how you might provide feedback on an author’s work. You should, of course, always tailor your review to the paper in question and the specific requirements of the journal and the editor.

Positive comments

The manuscript is well-written in an engaging and lively style.

The level is appropriate to the journal’s readership.

The subject is very important, it’s currently something of a “hot topic”, and this study makes significant contributions.

This manuscript ticks all the boxes I have in mind for a paper in this journal. I have no hesitation in recommending that it be accepted for publication after a few typos and other minor details have been attended to.

Given the complexity involved, the author has produced many positive and welcome outcomes. The literature review offers a useful overview of current research and policy, and the resulting bibliography provides a very useful resource for current practitioners.

This is a well-written article that identifies an important gap.

While this study is largely confirmatory, it is still a useful and welcome contribution.

I have checked over the methods and the supplementary data, and I found the study to be well carried out and appropriately controlled, with no obvious errors.

Constructive feedback

The abstract is very lengthy and goes into detailed accounts that are best suited for the article’s main discussion sections. I suggest the author reduces this section to keep only the most important elements.

I would strongly advise the author to rewrite their introduction, analysis, and discussion to produce a more contextualized introduction to…

The authors have used X approach and therefore I would expect to see additional controls/an explanation of the ethical approvals/deposition of the data in a public database. It is essential that the authors provide this information.

Citations to several important articles need to be added, as follows …

The data shown in table 1 and figure 3 appear to indicate X, whereas the Results section states Y. The authors should carefully check …

This research reveals an interesting finding about … However, I would like to see more discussion of exactly what this finding means and its implications.

I would have wished to see more information on …

I don’t think that this article contains enough robust data to evidence the statement made on page X, lines Y–Z. This should be toned down.

This discussion could be expanded to explain…

The author could strengthen the paper by…

The paper would be significantly improved with the addition of more details about…

Unfortunately, I have identified a potential major flaw in the work, which I believe will be difficult to resolve unless the authors are able to do the following additional analyses …

To make this paper publishable, the author needs to respond to the following substantive points…

Linguistic alterations

This paper would benefit from some closer proofreading. It includes many linguistic errors (e.g. agreement of verbs) that at times make it difficult to follow. It may be useful to engage a professional English language editor following a restructuring of the paper.

The paper would benefit from stylistic changes to the way it has been written for a stronger, clearer, and more compelling argument.

There are a few sentences that need rephrasing for clarity.

Make a recommendation

Once you’ve read the paper and have assessed its quality, you may need to make an overall recommendation to the editor to help them make a decision. The specific options used by a journal will vary, but the key recommendations are:

Accept : The paper is suitable for publication in its current form.

Minor revision : The paper will be ready for publication after light revisions. Please list the revisions you would recommend the author makes.

Major revision : The paper needs substantial changes such as expanded data analysis, widening of the literature review, or rewriting sections of the text.

Reject : The paper isn’t suitable for publication in this journal, or the revisions needed are too extensive for the submission to continue being considered in its current form. It is helpful to the editor if you can explain (in confidential comments if necessary) whether your recommendation is based upon the level of advance or whether it is due to technical flaws.

When authors make revisions to their article, they are asked to include a list of changes and any comments for the reviewers.

The revised version may be assessed by the editor if only minor revisions were requested or may be returned to the original reviewers if available. You will then be asked to affirm whether the revisions are satisfactory.

STEM research article checklist

Arts and humanities reviewer checklist

Further resources

Reviewer training

Peer review and your career

FAQs during review

research paper peer edit

Research paper editing

How to improve a research paper.

Once you’ve written your paper, the next important step is to make your paper better. This step includes research paper editing and it should be completed before deciding to submit your work.

Read on for further information and guidance on how to edit your manuscript.

What is editing a paper?

This is the process of evaluating and making changes to your paper before submitting to your target journal. Editing is a big task, but it is a crucial part in your publishing journey. Most successful publications have been through several rounds of editing.

Benefits of editing

The importance of editing after writing your paper is to make sure that it is persuasive and well-rounded to the reader. No matter how significant your research is, to be successful during the  peer review  process your manuscript must be  properly edited . 

The effectiveness of your writing style and clarity of your work can be significantly improved by good editing. The purpose of the editing step is to make sure your paper is written in an order that communicates your research, and your ideas are presented in the best way.

English language editing  particularly targets passive voice writing and run-on sentences for removal or correction.

To produce a research paper that will make an impact on your target readers, you should understand the kind of editing your paper needs and how editing works in the process of  preparing your manuscript for submission .

research paper peer edit

Revising and editing are sometimes used interchangeably but this is not the case, there is a difference between revising and editing.

Difference between revising and editing

Error type Revising Editing
Grammar errors X
Spelling errors X
Punctuation errors X
Typographical errors X
Logical flow X
Unnecessary information X
Suitable for audience X
Run-on sentences X
Word choice for audience X
Adding important details X
Clarifying views X
Improving idea presentation X
Structure & organization X X

Types of editing  

There are few different types of editing your research paper might need, they will all help you to avoid mistakes, make your paper easier to read, and help you meet journal requirements.

Some researchers believe that they only need to edit their work for spelling mistakes and grammar, but you must also  have the right structure and presentation for your paper , to increase your chances of publication success.

Content editing This analyzes the organization and presentation of your research. This editing process encourages you to answer questions about your paper like; does the paper make sense? Does it have a good flow? Are the arguments clearly developed and communicated? Are there any major logical gaps?  

Copy editing When you are copy editing your research paper, you’ll make corrections to spelling and punctuation, focusing on grammar, word choice, and enhancing your writing quality. 

Line editing The ‘line-to-line’ check of your research paper’s word choice and writing impact, makes this process like copy editing. Here you will make changes to your work that will give you a strong position paper. Look out for phrasing that sounds imitative and fix run-on sentences. Focus on clarity and simplify your writing so that the meaning is clear and not overly complex.

Mechanical editing Now that your paper has been edited for structure, content, coherence, style, flow, grammar, and word choice, it’s time for a final, but very important editing step. Mechanical editing makes sure that your paper conforms perfectly to the style guide of your chosen journal.

After your paper has been through all these different types of editing, you will be left with a well-presented journal article. You will demonstrate  good use of language  and could stand a much greater chance of being accepted by your target journal.

Expert help for your manuscript

Taylor & Francis Editing Services offers a full range of pre-submission manuscript preparation services to help you improve the quality of your manuscript and submit with confidence.

How to edit 

Now you know about the different types of editing, how should you approach editing your paper?

Correcting your own writing is known as self-editing. This process helps you take a critical look at your manuscript, making changes to your draft until it is in the best possible shape.  

The self-editing process

Understand your draft The purpose of your first draft is to put all your information into readable, clear sentences and paragraphs. This step can be referred to as revising. It requires looking at the “big picture” of your writing. While it takes a little longer to edit from printed work, printing your manuscript allows you to see if there is deviation from what you intended to write and what you typed. This will refresh your eyes and help you become “detached” from your own work. Quickly read through the paper once, highlighting areas of concern with your red pen. 

Take a break After reading through your printed work, it is time to take a break from it. It may seem most efficient to continue working due to a deadline, it will not be the most effective. Staying away from your paper allows you to revisit the work with a fresh set of eyes.

Read for structure If you have not read your paper out loud yet, it is time to do so. Be intentional about listening for the flow, structure, and organization of your paper. If something does not make sense or you find understanding difficult, mark the section, and move on. Read it out loud yourself or have someone read it to you. Hearing your content gives you a different way of reviewing. When you have finished, edit your marked errors.

Read for grammar and punctuation Checking for grammar and punctuation mistakes are part of the editing process most authors focus on. In this step you will be carrying out detailed language checks. As you write more papers, you will get better understanding of your tone and writing style. This will help you to identify the mistakes that you tend to make most often. 

Think like a reviewer To self-edit effectively, assume the role of a person who has never read your paper before. This will help to put you in a state of mind to find possible issues that can cause the paper to be rejected.

research paper peer edit

Have someone else read your work This is not always necessary, but it is helpful. Getting a fresh set of eyes on your content can highlight mistakes you may not have realized.

Review Make the necessary changes and read through it once more. Check your citations. Get confident in your sentences and paragraph breaks.

Hire a professional Remember that editing is a two-step process. Once you’ve completed your own edits, using the above guidance, you may still require a  professional paper editor  to polish and perfect your manuscript for a successful submission. 

Did you know?

With  Taylor & Francis Editing Services , you can be rest assured that your paper will stand out to journal editors – for all the right reasons – helping make sure you maximize the impact of your research and improve the quality of your manuscript.

Related resources

What makes a good research paper

How to prepare your article for submission

Improve your submission experience

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A Framework for Teaching Students How to Peer Edit

Giving meaningful feedback on a peer’s work doesn’t come naturally to students. Try these tips to help students hone their editing skills.

Teenagers help each other with homework

Too often, asking students to edit each other’s writing results in superficial commentary. Many students are uncertain about how to provide meaningful feedback on a peer’s work. 

One way to make peer review more effective is by scaffolding it, or breaking down the practice into several classes where students critique each other’s work in a more focused, incremental manner. Scaffolding allows students to identify and address a single type of error in an allotted time period. While it is a valuable process for all students, it is especially useful for English-language learners and learning-support students, who benefit from breaking tasks and information into more manageable components. 

Deconstruct Constructive Criticism

Students need to learn how to give and receive criticism in a productive and respectful manner. Before embarking on a class-wide peer review activity, teachers might underscore the importance of responses that are forthright and civil. Mastering the art of giving valuable feedback that doesn’t offend will benefit students in nearly every professional and personal relationship they maintain. 

Start by breaking down the two words: constructive and criticism . What do these words mean by themselves? What synonyms might apply to each word? Ask students to think of examples of ways they might offer constructive criticism on a peer’s writing. They can be as simple as “Remember to capitalize proper nouns” or “Restate your thesis in your final paragraph.” Underscore to students that the criticism must be specific and helpful. “Good job!” doesn’t suffice. Write their responses on one or two poster boards, and place them where students can see them and refer back to them throughout the process. 

Provide samples of criticism for students to emulate. You may want to advise learners to attach positive feedback with constructive criticism. For example, “Your hook poses a good question, but it contains several grammar errors” or “You inserted this quotation correctly.” 

As there is no definitive guide to constructive criticism, teachers and students are encouraged to discuss what constitutes responsible feedback to find a definition and standards that best suit the class.

Set Clear Plans

In the same way that instruction often demands that educators create the assessment first, teachers should prepare for the peer review at the beginning of any writing assignment. A scaffolded peer review can be time-consuming, so consider the length of the writing assignment to be assessed when making a determination about the class time required. 

Before assigning writing, consider what writing skills you want your students to learn, review, or practice. The objectives will vary by class, and they should be articulated to students from the outset. Some teachers may have the class focus on writing an effective thesis, incorporating quotations, or adding in-text citations. In other classes, the objective may be reviewing capitalization or comma usage. Identify the skills that students are expected to practice writing and finding in each other’s papers.

Facilitate the Process

Scaffolding the peer review provides an opportunity for students to read a piece multiple times to assess different elements of writing. First the class reviews the objective as a whole group. Then peer pairs review their individual writing with a focus on the defined learning objective. 

Some students may be reluctant to criticize peers’ work. Consider choosing peer-review partners instead of letting the students pick. This might cut down on students’ being fearful of offending their friends. Also, if the debrief period is generating little discussion, ask students to debrief with their partners as opposed to in front of the class. Give students a set of debrief prompts to focus their discussion, such as “Discuss the corrections you made.” 

Encourage students to refer to the posters regarding constructive criticism examples, especially if someone has given an impolite criticism. 

Debrief as a Class

After the pair reviews, debrief by discussing the findings as a class. The debrief can be an open-ended session in which the teacher encourages students to ask questions and voice misunderstandings about both writing and critiquing. The debrief can also be more structured and incorporate specific questions, such as “What is a challenge an editor or peer reviewer might face?” or “What is one element of your writing you wish to improve upon?” The debrief can also take the form of a small writing assignment, such as a reflective paragraph on the peer review process in which students summarize what they have learned as an editor and proofreader.

We want our students to be proficient writers and thinkers. Reviewing a peer’s work can help young people better understand the often difficult process of writing by challenging them to adopt a dynamic new role as critic.

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Peer-editing Practice in the Writing Classroom: Benefits and Drawbacks

Profile image of Ann Deni

2011, Advances in Language and Literary Studies

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PROJECT (Professional Journal of English Education)

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This research aimed at improving students’ skills of writing for the eleventh grade students of SMK TI Pembangunan Cimahi through the use of peer editing. It is expected that peer editing can be used to improve the students’ writing skill in recount text in SMK TI Pembangunan Cimahi. This research was an action research study that consisted of two cycles. In doing the research, the researcher involved 33 students of Class XI as the respondent of the research. The data was collected by observation and writing test. The result of this research indicated that peer editing improve student writing skill from cycle to cyle. It means peer editing technique can improve students writing skill.The researcher also found that peer editing was appropriate technique for students grade XI in SMK TI Pembangunan Cimahi. Beside of learning writing it self, by using this technique student also learnt how to be cooperative in pair, because peer editing was done by pairing. The students’ writing ability...

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AbstrakPenelitian ini bertujuan untuk mengetahui bagaimana teknik Peer Editing dapat meningkatkan penulisan mahasiswa untuk mahasiswa semester dua program studi pendidikan Agama Islam di IAIN Pontianak pada tahun akademik 2016/2017. Penelitian tindakan kelas ini dilakukan dalam dua siklus. Setiap siklus terdiri dari empat tahapan; perencanaan, tindakan, mengamati, dan evaluasi. Subjek penelitian adalah mahasiswa kelas A yang terdiri dari 34mahasiswa dengan perincian 10 mahasiswa pria dan 24 mahasiswa wanita. Penelitian ini menggunakan observasi dan pengukuran sebagai teknik pengumpulan data. Dalam mengumpulkan data, penulis menggunakan data kualitatif dan kuantitatif. Data kualitatif diambil dari daftar observasi, catatan lapangan, dan perekam sementara data kuantitatif diambil dari tes menulis mahasiswa. Kemudian, dalam menganalisis data, penulis menggunakan analisis deskriptif kualitatif untuk data kualitatif dan statistik deskriptif dengan data kuantitatif.Berdasarkan hasil ch...

JEELS (Journal of English Education and Linguistics Studies)

Peer and self editing strategies are social and metacognitive strategies used in the steps of sharing, revising, and editing in writing. The objective of the study is to see how peer and self editing strategies are able to improve students' writing skill. 64 students-participants were actively involved in this classroom action research. Peer editing worksheet, self editing worksheet, and test sheet were used as the instruments. The results showed that students' writing skill improved in all elements: the quality of format, punctuation and mechanics, content, organization, and grammar and sentence structure. They had achieved the criteria of success as determined. It can be concluded that peer and self-editing strategies are able to improve students' writing skill.

Journal of Scientific Research, Education, and Technology (JSRET)

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This study aims to solve the problems found in students’ writing especially the errors in the use of authorial and secretarial aspects to the 11th grade students from OTKP major SMK Negeri 1 Teluk Keramat in the academic year 2021/2022. Using Classroom Action Research (CAR), this study tried to improve students’ writing skill of personal letter by the use of the peer-editing technique. The participants of this research were the 11th grade students of Otomatisasi dan Tata Kelola Perkantoran (OTKP) major. The data were collected through observation and documentation. The data were analyst using quantitative and thematic analysist technique. The results showed that the use of the peer-editing technique successfully improved students’ writings skill of personal letter. It was found through the process of using the peer-editing technique, students were likely to give various types of comments and suggestions in the text structure, grammar, vocabulary, punctuation, and spelling. The impro...

Wanastra: Jurnal Bahasa dan Sastra

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Abstract: Using Peer Editing and Peer Feedback Techniques in Writing to Private University Students. Objectives: this reserach is to find out whether there was any significant difference betweeen the students are taught by using Peer Editing and Peer Feedback Technique. Methods: Quasi-Experimental method was used by providing two groups as an experimental group and control group. The total of students from both groups was 100 students. The data were analyzed by paired sample t-test and independent sample t-test. Findings: The result of paired sample t-test innexperimental and control group showed that value of p-value was .000. At the signicance level p > 0.05 for two tailed test. Conclusion: the use of Peer Editing and Peer Feedback technique can improve students’ in writing narrative text. Keywords: peer-editing technique, peer feedback technique, writing skill. Abstrak: Menggunakan Teknik Peer Editing dan Peer Feedback dalam Menulis untuk Mahasiswa Universitas Swasta. Tujuan:...

Journal of Language and Linguistic Studies

Inspired from problematic nature of writing, this study adopted an action research through peer editing as a way of developing writing skills of students at an ELT department. This study was designed through the specific stages of an action research which are planning, action, observation and reflection. In planning and action stages, the researchers designed general and specific criteria to follow during the cycles, and they applied these criteria accordingly. In observation stage, the peer editing processes in specific cycles were observed. The researchers used cycles at this stage. These cycles were application processes which were followed step by step during peer editing. In reflection stage, reflections of the participants on peer editing in writing classes were gathered through a form. Qualitative data collected from participants were analyzed and reported descriptively at the end. The reflections were categorized as before and after writing classes, advantages and disadvantages of peer editing. In conclusion, peer editing in writing classes affects foreign language learners positively, and peer editing can be used in writing classes as an alternative way of developing ELT students' writing skills.

International Journal of Social Science and Humanities Research

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This study assessed the effectiveness of peer editing strategy for Senior High School students engaged in English academic writing classes at University of Cebu

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T his study was aimed at revealing students’ essay writing skill, describing the improvement of writing aspects, and finding out whether or not the use of peer editing was effective to improve the students’ writing skill. This reseach was experimental study using nonequivalent control group design. The population of this research was all the fifth semester students of English Education Program of Muhammadiyah University of Purworejo. The researcher used two classes as the research samples. As the experimental group, the researcher took students of VA class who were taught by peer editing. Then, the researcher involved students of VB class as the control group. The reseacher conducted a series of treatment from August to November 2014. The researcher used a writing test to collect the data. Descriptive statistics and inferential statistics were employed to analyze the data. After analyzing the data, the researcher obtained some find- ings. First, the students’ writing score was 71.2...

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This research discusses the implementation of peer editing in teaching-learning writing to the eleventh grade students at SMA Negeri 1 Surakarta 2014/2015 academic year. The research uses qualitative approach in the form of case study. The subject of this research is the English teacher and the eleventh grade students of SMA Negeri 1 Surakarta in the academic year of 2014/2015 consists of 33 students. This research focuses how Peer Editing is implemented in writing class and how effective Peer Editing is implemented in teaching writing skill to the eleventh grade class. The data were collected through observations, interviews and documents.The result of the research reveals two major findings which consist of: (1) the description of the implemented peer editing in writing class at the eleventh grade class and (2) the effectiveness of peer editing in teaching-learning writing to the eleventh grade class.Based on the research findings, it can be summarized that the implementation of p...

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Transporting precious cargo using the body’s own delivery system

Advances ‘get us one step closer to the ultimate goal of targeted biological drug delivery’

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  • Release Date: July 16, 2024

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  • Delivery systems in body continuously move materials between cells
  • Hijacking these systems allowed scientists to improve loading and delivery of therapeutic proteins
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  • Engineered molecules loaded up to 240 times more protein than other loading methods

EVANSTON, Ill. --- Each cell in the body has its own unique delivery system that scientists are working on harnessing to move revolutionary biological drugs — molecules like proteins, RNA and combinations of the two — to specific diseased parts of the body.

A new study from Northwestern University hijacked the transit system and sent tiny, virus-sized containers to effectively deliver an engineered protein to its target cell and trigger a change in the cell’s gene expression. The success came from encouraging engineered proteins to move toward a specific cell membrane structure that the researchers found increased a protein’s likelihood of latching onto the container.

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The research combines work from two labs in Northwestern’s Center for Synthetic Biology : those of biomedical engineer Neha Kamat and chemical and biological engineer Josh Leonard . The Kamat lab has largely focused on the design of synthetic containers and uses biophysical principles to control molecules targeting other cells.  Leonard’s lab develops tools to build these natural delivery containers, termed extracellular vesicles (EVs).

“We were interested in applying some of the biophysical insights that have emerged about how to localize proteins to specific membrane structures so that we could hijack this natural system,” said Kamat, the paper’s co-corresponding author and associate professor at the McCormick School of Engineering. “In this study, we discover general ways to load drug cargo into these vesicles very efficiently while preserving their function. This might enable more effective and affordable extracellular vesicle-based biological medicines.”

The keys to this “cargo loading” approach are sites on cell membranes called lipid rafts. These regions are more structured than the rest of the membrane and reliably contain specific proteins and lipids.

“Lipid rafts are thought by some to play a role in the genesis of EVs, as EV membranes contain the same lipids found in lipid rafts,” said Justin Peruzzi, who co-led the study with Taylor Gunnels as doctoral students in Kamat’s lab. Gunnels’ work in the lab is ongoing, and Peruzzi, who completed his Ph.D., works as a scientist at a protein-based medicine company. “We hypothesized that if we engineered proteins to associate with lipid rafts, they may be loaded into the vesicles, allowing them to be delivered to other cells.”

The team used protein databases and lab experiments to determine that lipid raft-association is an efficient method to load protein cargo into EVs, enabling up to a stunning 240 times more protein to be loaded into vesicles.

After discovering this biophysical principle, the researchers demonstrated a practical application of the method. They engineered cells to produce a protein called a transcription factor, loaded it into EVs and then delivered it to a cell to alter the recipient cell’s gene expression — without compromising the protein’s function upon delivery.

Kamat and Leonard said the main challenge in loading therapeutic cargo into EVs is that the producer cell and the recipient cell are often at odds with each other. In the cell producing the EV, for example, you might engineer therapeutic cargo to associate tightly to a membrane to increase the chance it moves into a soon-to-be released EV. However, this same behavior is often undesirable in a recipient cell because delivered cargo stuck to a membrane might be nonfunctional. Instead, you might want that cargo to release from the EV membrane and move to the cell’s nucleus to perform its biological function. The answer was the creation of cargo with reversible functions.

“Tools that enable reversible membrane association could be really powerful when building EV-based medicines,” said Gunnels. “Although we’re not yet sure of the precise mechanism, we see evidence of this reversibility with our approach. We were able to show that by modulating lipid-protein interactions, we could load and functionally deliver our model therapeutic cargo. Looking forward, we’re eager to use this approach to load therapeutically relevant molecules, like CRISPR gene-editing systems.”

The researchers said they’re eager to try the approach with medicinal cargo for disease applications in immunotherapy and regenerative medicine.

“If we can load functional biomedicines into EVs that are engineered to only deliver those biomolecules to diseased cells, we can open the door to treating all sorts of diseases,” said Leonard, the co-corresponding author and a McCormick professor. “Because of the generalizability that we observed in our system, we think this study's findings could be applied to deliver a wide array of therapeutic cargos for various disease states.”

The paper, titled “Enhancing extracellular vesicle cargo loading and functional delivery by engineering protein-lipid interactions,” was supported by the McCormick Research Catalyst Program at Northwestern University, the National Science Foundation (grants 1844219 and 2145050) and NSF Graduate Research Fellowships (DGE-1842165).

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  22. Welcome to Turnitin Guides

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