of achievement
Concept of Long-Term Socio-Economic Development of Russia until 2020
and
Strategy for Innovative Development of Russia 2020
* In 2020, the share of organizations implementing technological innovations increased to 23% (up to 21.5% in industry). This growth is associated with a change in international recommendations on the statistical measurement of innovation, implemented by the OECD together with Eurostat (Oslo Manual). The value of the indicator for the Russian Federation for 2017, calculated according to the criteria of the 3rd edition of the Oslo Manual, amounted to 7.5%, when recalculated according to the criteria of the 4th edition of the Oslo Manual, it increased to 20.8%. The difference in the calculation is due to the use of three criteria for classifying an organization as innovative instead of one.
In the Concept of Long-Term Socio-Economic Development until 2020 (CLTD) 2 adopted by the Government of the Russian Federation in 2008, the task of Russia’s transition to the innovative development of the economy was set. In 2011, the Innovative Development Strategy was adopted, the purpose of which was to increase the innovative activity of business and the efficiency of the transformation of scientific ideas into technologies and market innovations, a state program for the development of science and technology was initiated, as well as a number of other decisions.
However, most of the targets of the CLTD-2020 and the Innovation Development Strategy were not achieved. In particular, domestic expenditures on R&D were planned in 2020 at the level of 3% of GDP, but in fact amounted to only 1.1%. Actually, the indicator of R&D expenses relative to GDP (1%) has been stagnating for almost 13 years. The problems that had accumulated over the years sharply escalated under the conditions of the hybrid war launched by the West against Russia, including actions to isolate the Russian scientific community from world science and a technological blockade.
What resources does Russia have in this war of minds and technologies, and how should the management of the scientific and technological complex be restructured in order to win and lift the country?
Comparative potential and effectiveness of the scientific and technological complex of Russia and other countries: relative and absolute dimensions. If in 2008 we were approximately on the same level with China in terms of the relative level of R&D expenses, now China has increased spending to 2.4% of GDP, despite the fact that its GDP is 5.5 times higher than in Russia ( Table 2 ). In the United States, R&D expenses are 3.4% of GDP, in South Korea 4.8% of GDP. Although Russia now ranks 9th in the world in terms of R&D expenses (in terms of purchasing power parity), it is 12.1 times behind China and 15 times behind the United States, and there are all the prerequisites for this gap to widen [ 2 ]. In the context of fierce technological rivalry and the hybrid war unleashed against Russia by the collective West, such an imbalance in power becomes threatening.
Comparative global dynamics of R&D expenses
Country | R&D expenditures based on PPP, billion dollars | R&D expenses, % of GDP | Including government R&D expenses, % of GDP | |||
---|---|---|---|---|---|---|
2008 | 2020 | 2008 | 2020 | 2008 | 2020 | |
Israel | 8.7 | 19.8 | 4.3 | 5.44 | 0.5 | 0.5 |
Republic of Korea | 43.9 | 112.9 | 3.0 | 4.81 | 0.8 | 1.1 |
USA | 407.2 | 720.8 | 2.8 | 3.45 | 0.8 | 0.7 |
Japan | 148.7 | 174.1 | 3.3 | 3.3 | 0.5 | 0.5 |
Germany | 81.2 | 143.4 | 2.6 | 3.14 | 0.7 | 0.9 |
China | 145.1 | 582.8 | 1.4 | 2.4 | 0.3 | 0.5 |
France | 46.6 | 74.6 | 2.1 | 2.35 | 0.8 | 0.7 |
Great Britain | 36.5 | 56.9 | 1.6 | 1.7 | 0.5 | 0.5 |
Czech Republic | 3.6 | 8.9 | 1.2 | 1.9 | 0.6 | 0.7 |
Russia | 30.1 | 47.9 | 0.97 | 1.1 | 0.6 | 0.7 |
Source: OECD, UK (PPP R&D expenses) 2019, Israel, Germany, France (Public R&D expenses, % of GDP) 2019.
If we evaluate R&D expenses taking into account the number of researchers, then the situation in Russia will be even less optimistic: in 2019, 1 researcher (in full-time equivalent) accounted for 3.5 times less research and development expenses than in the United States, and three times less than in Germany. According to this indicator, Russia occupies only 44th place 3 ( Table 3 ).
Place of Russia among the leading countries of the world
Country | R&D employees by country: 2020 (thousand person-years, full-time equivalent) | Country | Number of researchers by country: 2020* (thousand person-years, full-time equivalent) | Country | Domestic R&D expenses by country: 2020 billion dollars in terms of PPP | |
---|---|---|---|---|---|---|
1 | China | 4800.8 | China | 2109.5 | USA | 657.5 |
2 | USA | 1554.9 | USA | 1554.9 | China | 525.7 |
3 | Japan | 903.4 | Japan | 681.8 | Japan | 173.3 |
4 | Russia | 748.7 | Germany | 450.7 | Germany | 148.1 |
5 | Germany | 735.6 | Republic of Korea | 430.7 | Republic of Korea | 102.5 |
6 | India | 553.0 | Russia | 397.2 | France | 73.3 |
7 | Republic of Korea | 525.7 | India | 341.8 | India | 58.7 |
8 | Great Britain | 486.1 | Great Britain | 317.5 | Great Britain | 56.9 |
9 | France | 463.7 | France | 314.1 | Russia | 45.4 |
10 | Italy | 355.9 | Brazil | 180.0 | Taiwan | 44.0 |
11 | Brazil | 316.5 | Canada | 167.4 | Italy | 39.3 |
12 | Taiwan | 271.6 | Italy | 160.8 | Brazil | 36.3 |
13 | Canada | 238.1 | Taiwan | 159.2 | Canada | 31.0 |
* OECD data. Number of researchers: UK–2007, 2018, China—2012, Germany—2007.
Source: OECD, ANO VEB Institute.
The national project provided for Russia to maintain the 5th place in terms of the number of researchers in full-time equivalent among the leading countries of the world (according to the OECD) for the period from 2018 to 2021. However, according to the OECD, in 2020 the Republic of Korea overtook Russia in this indicator, shifting it to the 6th position in the rating. Thus, in 2020 Russia is ahead of China (the number of researchers in full-time equivalent is estimated at 2109.5 thousand people), the United States (1554.9 thousand people), Japan (681.8 thousand people), Germany (450.7 thousand people), Republic of Korea (430.7 thousand people). In Russia, this figure in 2020 decreased to 397.2 thousand people versus 400.6 thousand people in 2019. In the leading countries, the number of researchers is growing, while in Russia it has been declining for more than 20 years in a row.
The lag behind developed countries in the field of science and technology is quite large, which creates the preconditions for a “brain drain.” In Germany and the Czech Republic, the salary of scientific workers is 1.9 and 1.3 times higher than the corresponding Russian indicator (the gap for researchers is even higher). 4 However, the issue of brain drain is not so much a matter of wages, but rather of the opportunity to realize one’s potential, the status of a scientist and engineer in society, as well as the access to the global scientific and technological community.
The capital–labor ratio of the scientific sector in Russia today is comparable to that of the scientific sector in the Czech Republic ( Table 4 ).
Resources of science: position of the Russian scientific complex
No. | Country | R&D, billion dollars in terms of PPP | Capital-labor ratio, billion dollars | Number of researchers, thousand people | Researcher’s salary in 2021 in dollars according to glassdoor.com in terms of PPP * | Patents**, thousand items | Web of science publications, thousand items*** | |||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
2008 | 2020 | 2008 | 2020**** | 2008 | 2020***** | 2021 | 2008 | 2020 | 2008 | 2020 | ||
1 | USA | 407.2 | 720.8 | N/A | N/A | 10 242 | 429 | 496 | 327 | 606 | ||
2 | China | 145.1 | 582.8 | N/A | N/A | 2069.7 | 4393 | 204 | 1441 | 108 | 614 | |
3 | Japan | 148.7 | 174.1 | N/A | N/A | 890.7 | 951.0 | 6074 | 510 | 423 | 77 | 117.3 |
4 | Germany | 81.2 | 143.4 | N/A | N/A | 437.8 | 667.4 | 6501 | 172 | 168 | 83 | 162.5 |
5 | Republic of Korea | 43.9 | 112.9 | N/A | N/A | 300.1 | 558.0 | 4808 | 173 | 261 | 34 | 86.1 |
6 | France | 46.6 | 74.6 | 163.0 | 225.3 | 289.0 | 430.0 | 5436 | 62 | 64 | 62 | 105.4 |
7 | Great Britain | 407.2 | 56.9 | 59.6 | 61.8 | 377.2 | 535.5 | 5780 | 51 | 53 | 86 | 194.9 |
8 | Russia | 30.1 | 47.9 | 11.3 | 18.0 | 375.8 | 346.4 | 3581 | 31 | 30 | 28 | 84.9 |
9 | Israel | 8.7 | 19.8 | N/A | N/A | 4845 | 11 | 16 | 12 | 22.3 | ||
10 | Czech Republic | 3.6 | 8.9 | 12.8 | 12.3 | 44.2 | 65.1 | 4512 | 2 | 2 | 8 | 22.3 |
* Salary is estimated based on machine learning on the basis of millions of salaries from Glassdoor and latest government data sources.
** Patent statistics: https://www3.wipo.int/ipstats/IpsStatsResultvalue . Cited June 5, 2022.
*** Only web of science publications. The dynamics of the number of publications is calculated based on the data of the analytical system InCites (Clarivate Analytics) for Web of Science as of October 31, 2021. A publication means three types of documents indexed in Web of Science: an article, a review and a proceedings paper.
**** France’s capital-labor ratio—2019 data.
***** Number of researchers in China, Germany, France, UK in 2019.
Source: OECD, Rosstat, National Research University Higher School of Economics, ANO VEB Institute.
Naturally, not only the total capital–labor ratio is important, but also the technical equipment of researchers, since the potential capabilities of organizations in obtaining world-class scientific results and their competitive prospects largely depend on the availability of modern scientific equipment. The Decree of the President of the Russian Federation No. 204 of May 7, 2018 set the strategic task of updating at least 50% of the instrumentation base of the leading research and development organizations by 2024. In 2020, less than half (39%) of technical equipment was new equipment under the age of five years. However, most of the research organizations, especially those of an applied nature, remained outside the national project and, accordingly, without incentive measures to update the experimental and testing base.
Traditionally, the effectiveness of scientific activity is considered through publication and patent activity. In 2020, Russia ranked 14th in terms of the number of publications in Web of Science and 8th in Scopus; 10th place in terms of the number of applications for a patent for inventions ( Table 5 ). Not the highest result, but its level relative to R&D expenses is very decent. With a significantly lower share of spending on science in GDP, the publication activity of scientists in Russia corresponds to and even exceeds similar values for other developed countries. Accordingly, the relative “cost” of one scientific publication in Russia is lower, which is confirmed by the RSF estimate of the “cost” of publications at the expense of scientific grants allocated by the Foundation, about 2 million rubles for an article in a top-rated journal.
Comparative efficiency of scientific activity
No. | Country | R&D expenses, % of GDP | Capital–labor ratio per researcher, million dollars* | Patents per researcher** | Publications per researcher | ||||
---|---|---|---|---|---|---|---|---|---|
2008 | 2020 | 2008 | 2020 | 2008 | 2020 | 2008 | 2020 | ||
1 | Israel | 4.3 | 5.4 | N/A | N/A | N/A | N/A | N/A | N/A |
2 | Rep. Korea | 3.0 | 4.8 | N/A | N/A | 0.6 | 0.5 | 0.1 | 0.2 |
3 | Japan | 3.3 | 3.3 | N/A | N/A | 0.6 | 0.4 | 0.1 | 0.1 |
4 | Germany | 2.6 | 3.14 | N/A | N/A | 0.4 | 0.3 | 0.2 | 0.2 |
5 | USA | 2.8 | 3.45 | N/A | N/A | 0.4 | 0.3 | 0.3 | 0.4 |
6 | China | 1.4 | 2.4 | N/A | N/A | 0.1 | 0.7 | 0.1 | 0.3 |
7 | France | 2.1 | 2.35 | 0.6 | 0.5 | 0.2 | 0.1 | 0.2 | 0.2 |
8 | Great Britain | 1.6 | 1.7 | 0.2 | 0.1 | 0.1 | 0.1 | 0.2 | 0.4 |
9 | Czech Republic | 1.2 | 1.9 | 0.3 | 0.2 | 0.03 | 0.03 | 0.1 | 0.1 |
10 | Russia | 0.97 | 1.1 | 0.03 | 0.1 | 0.08 | 0.09 | 0.1 | 0.2 |
* France—capital–labor ratio per researcher, 2018.
** USA (2008, 2020), China (2008)—patents per researcher (thousand person-years, full-time equivalent).
Source: OECD, Rosstat, ANO VEB Institute.
This indirectly testifies to the good performance of the domestic scientific sector, at least in the field of fundamental science, in contrast to the opinion often expressed in the expert community and in government about the inefficiency of Russian science.
The low number of patents (in 2020, Russia was not among the top ten countries), as well as the extremely low share of high-tech exports (the ratio of R&D and high-tech exports) really indicate significant problems with the development of the applied science sector responsible for broadcasting the results of fundamental science in pilot and serial production with the involvement of business funds represented by public and private companies and corporations ( Fig. 1 ). It should be taken into account that such exported high-tech products as nuclear fuel and reactors, according to the international classification, do not belong to high-tech exports. Nevertheless, this does not change the overall low rating of Russian high-tech exports.
Comparison of the level of development of the country, R&D expenses and technological exports, 2020 (the size of the “bubble” is the share of high-tech exports in exports).
For all the importance of the science-intensive export factor, it is necessary to take into account the significant structural difference between the Russian scientific and technological complex and other developed countries. Historically, it was focused not on exports, which were mainly raw materials, but on solving the internal problems of the state, including those related to defense capability. The structure of scientific publications, as well as patent activity in Russia, is largely concentrated in the fields of mathematics, physics and engineering, in contrast to medicine and information technology, which are a priority in the West.
We have yet to create a truly realistic comprehensive system for assessing the achieved scientific and technological potential instead of fragmentary indicators borrowed from Western experience. We need new criteria (except for publications and patents) and a new science assessment system based on a qualified expert assessment, indicators of work with the industry, promotion of R&D results by levels of technological readiness. According to the President of the Russian Academy of Sciences A. M. Sergeev, “the main result will not be an article, but an expert assessment of specialists and the final product”. 5
In various coordinate systems of scientific and technological activity, Russia occupies from 6th to 12th place ( Table 6 ). According to a comprehensive assessment of ANO VEB Institute, 6 in 2019 we have an honorable 7th place in the world table of scientific ranks.
Comprehensive assessment of the place of the Russian scientific complex in the world
Country | Resources | Results | Top 500 universities | Final place | ||
---|---|---|---|---|---|---|
DRDE | Researchers | Publications | Patents | |||
USA | 1 | 2 | 1 | 2 | 1 | 1 |
China | 2 | 1 | 2 | 1 | 5 | 2 |
Japan | 3 | 3 | 6 | 3 | 6 | 3 |
Germany | 4 | 4 | 4 | 5 | 3 | 4 |
South Korea | 5 | 5 | 13 | 4 | 8 | 6 |
France | 6 | 8 | 7 | 26 | 7 | 10 |
Great Britain | 7 | 7 | 3 | 6 | 2 | 5 |
Russia | 8 | 6 | 12 | 11 | 7 | 7 |
Italy | 9 | 9 | 8 | 10 | 10 | 8 |
Canada | 10 | 10 | 9 | 13 | 6 | 9 |
Spain | 11 | 11 | 11 | 22 | 10 | 12 |
Netherlands | 12 | 13 | 15 | 8 | 9 | 11 |
Switzerland | 13 | 18 | 19 | 7 | 13 | 13 |
Sweden | 14 | 14 | 20 | 12 | 13 | 14 |
Belgium | 15 | 15 | 22 | 16 | 14 | 15 |
Poland | 16 | 12 | 17 | 29 | 19 | 17 |
Austria | 17 | 16 | 26 | 15 | 16 | 16 |
Singapore | 18 | 23 | 33 | 25 | 18 | 20 |
Denmark | 19 | 20 | 24 | 17 | 16 | 18 |
Czech Republic | 20 | 19 | 27 | 34 | 18 | 21 |
Finland | 21 | 21 | 36 | 20 | 13 | 19 |
Norway | 22 | 24 | 32 | 28 | 17 | 22 |
Ireland | 23 | 25 | 44 | 27 | 16 | 23 |
Portugal | 24 | 17 | 25 | 74 | 17 | 25 |
Hungary | 25 | 22 | 48 | 39 | 20 | 24 |
Slovenia | 26 | 27 | 56 | 56 | 20 | 28 |
Slovakia | 27 | 26 | 49 | 54 | 20 | 26 |
Luxembourg | 28 | 28 | 76 | 31 | 20 | 27 |
In general, in terms of the level of scientific and technological activity, Russia is approximately in the same place as in terms of GDP in terms of purchasing power parity. Such positioning is more characteristic of an economy that is trying to gain a foothold on what has been achieved, with the risk of losing its occupied place, than for an economy that is breaking through upwards.
Science and technology policy priorities in Russia: controversial searches. What are the reasons for this huge discrepancy between ambitious goals and modest results? The year of science has ended, but there has been no visible scientific and technological upsurge.
The first reason is chronic underfunding, usually explained by insufficient efficiency, and by reference to the high share of public funding compared to Western countries. True, in terms of absolute volumes, both state and, even more so, private funding per employee or per key area of research and development is extremely small. At the same time, Russian private business with large incomes, unlike Western countries, is concentrated mainly in the fuel and energy and raw materials sectors, where the relative level of R&D expenses in the West is also low. On the whole, in terms of the relative (to revenue) level of R&D expenses, but not in absolute terms, our leading industrial companies are not inferior to Western ones.
Despite the implementation of the Presidential Decree to increase the salaries of scientists included in the target categories, the prestige of scientific activity is not increasing, while the inflationary surge in the scientific and educational sphere in 2022 has so far remained without adequate compensation. All this contributes to the continuation of the trend towards a reduction in the number of scientists and researchers. There is still a shortage of modern scientific equipment, especially of domestic design, with a limited scale of implementation of megascience projects in Russia, despite the PIK and SKIF projects.
The second reason, perhaps more important, is the lack of a systematic, consistent policy for the development of science and technology and a “lost aim of priorities and principles.” We are persistently trying to develop the scientific and educational sphere along the American path, relying on the leading role of universities in the development of science and the formation of a venture capital market as the basis for innovative technologies and projects. However, the Russian tradition is closer to the German model and its advantage, rather than disadvantage, is the presence of powerful academic institutions and industry science, including in the form of state research centers (SRCs) [ 3 ].
Despite repeated attempts to reform the field of science and create a modern innovation system, one can speak of a crisis in the management system of the country’s scientific and technological complex.
The list of priority areas and critical technologies has been updated long time ago, in 2002, 2006, 2011 and 2015. 7 Despite the fact that the number of positions in the list of critical technologies has consistently decreased, none of the lists was accompanied by an indication of additional funding for the priorities included in the list, as a result of which it did not become a real tool for highlighting the most important areas, and is mainly used for ritual references in the preparation of various scientific programs and funding applications. In the Strategy for Scientific and Technological Development of the Russian Federation (SNTD), a list of seven areas appeared, which actually began to be used as a priority. They were based on an analysis of the “big challenges” facing the country, and they were supposed to be specified at the next stage, which was never implemented.
In the new version of the state program “Scientific and technological development of the Russian Federation” (SP STD), 8 an attempt was made to formally align projects and financing instruments under the logic of priorities set in the STD Strategy. To do this, the research work that was previously carried out by line ministries is rather schematically combined into large blocks to correspond to the various priority areas of the Strategy, which in essence is a matter of classification, but not the allocation of real priorities for the purpose of their priority funding. The old system of determining the priorities of technological development by the Presidential Decree does not work, and a new integral system has not been formed. Under these conditions, the plans for scientific research (government order) do not meet the breakthrough tasks and global challenges facing the country, and are largely guided by the principle “by what has been achieved.”
A partial selection of priorities based on forecasting new markets was also carried out during the formation of the National Technology Initiative (NTI) [ 4 ]. The Presidium of the Council under the President of the Russian Federation for the Modernization of the Economy and Innovative Development of Russia approved seven roadmaps: Autonet, Aeronet, Marinet, Neuronet, Technet, Healthnet, Energynet. To date, the number of NTI directions has increased to 13, Foodnet, Safenet, Edunet, Sportnet, Homenet, Wearnet have been added. However, the fashion and e-sports markets can hardly claim the role of a priority area for research and development.
In 2022, at a meeting of the Council for Science and Education under the President of the Russian Federation, three new most important innovative projects of national importance were announced, which can also be considered as a choice of priorities:
— Russian scientific and technological platform for rapid response to infectious diseases.
— Creation of the Unified National Monitoring System for Climatically Active Substances.
— Low-carbon closed-loop energy.
Despite the relevance of these topics, taking into account the challenges of the COVID-19 epidemic [ 5 ] and the tasks of adaptation to climate change, in the context of a hybrid war, their priority is relatively reduced.
The now adopted new SP STD (funding is approved only until 2024) for 2022 provides for funding in the amount of more than a trillion rubles, but this is ensured mainly by including in the SP STD the amount of funding for research and development previously ordered by line ministries—the Ministry of Industry and Trade of Russia, the Ministry of Health of Russia and other departments. In other words, the apparent increase in funding for the new state program is associated with the merging into one program of all projects and major events, in the name of which there was the word “scientific …” from the rest of the state programs, while the coordination of all the former industry R&D of the Ministry of Education and Science has not been worked out yet. Such an association does not imply real coordination of projects. In nominal terms, until 2024, an average annual growth of funding by 0.9% per year is planned, which means a decrease in funding in real terms (in the old program for 2020, an increase of 2.7% per year was planned) ( Table 7 ).
State program for the development of science and technology (old and new), billion rubles
Indicator | 2022 | 2023 | 2024 | |||
---|---|---|---|---|---|---|
old | new | old | new | old | new | |
SP STD | 838.5 | 1075.5 | 881.8 | 1138.9 | 957.2 | 1173.5 |
FP | 119.1 | 251.2 | 140.7 | 282.3 | N/A | 262.4 |
Departmental project | 0.02 | 75.9 | 0.02 | 64.4 | N/A | 61.3 |
OM | 719.4 | 741.0 | N/A | |||
FTP | 0.6 | 0.6 | N/A | 0.6 | ||
Complex of process measures | 744.8 | 788.6 | N/A | 846.2 |
Source: ANO VEB Institute.
In our opinion, in the new SP STD, taking into account the experience of NTI and road maps, it is necessary to single out specific scientific and technological areas, ensuring their priority funding [ 6 ]. A significant part of the scientific community agrees that these are artificial intelligence, microelectronic, photonic and quantum technologies, new materials and additive manufacturing, the Internet of things and 5/6G communications, medical technology and pharmacology, genetic and biotechnologies. 9
Management dramas or barriers in the circulation of ideas and innovations . The development of science is the responsibility of the Ministry of Science and Education, while technological areas are the responsibility of line ministries, from the Ministry of Industry and Trade to the Ministry of Defense. The Academy of Sciences, although it did not turn into a club of scientists, lost the status of a scientific organization after the reform of 2013 and has rather an informal influence on the management of the scientific and technological process.
By Decree of the President of the Russian Federation No. 143 of March 15, 2021, On Measures to Improve the Efficiency of the State Science and Technology Policy, the functions of determining the strategic goals, objectives and priorities of the scientific and technological development of the Russian Federation are assigned to the Council under the President of the Russian Federation for Science and the permanent Commission on Scientific and Technological Development of the Russian Federation under the Government of the Russian Federation. However, the new functions and the creation of the commission did not change the nature of the management of the scientific and technological complex. The plurality and diversity of priorities at various levels indicate the absence of a coordinated system for determining the scientific and technological goals of these priorities, which then inevitably manifests itself both in their resource provision and in the concentration of managerial efforts in accordance with the designated goals. The expert potential of the Academy of Sciences is used to a small extent when considering key strategic decisions and large-scale scientific, technological and spatial projects in managing the development of science and technology.
The Ministry of Education and Science, currently mainly focused on higher education issues and the scientific agenda, especially applied science, is on the sidelines, while the importance of developing scientific and technological groundwork in the activities of sectoral departments is declining under the influence of a wave of current sectoral problems. In contrast to Soviet times, the coordination of scientific and technological developments in the civil and military spheres is also at a low level. For all the relativity of international university rankings, despite additional funding in the amount of 80 billion rubles, none of the universities participating in the 5/100 project has made it into the top 100 world rankings.
An analysis of the volume and structure of financing of the state program “Scientific and technological development of the Russian Federation” until 2024 also indicates that its main expenses go to the implementation of the subprogram “Ensuring the global competitiveness of Russian higher education”–ensuring current expenses for the implementation of educational programs and activities of higher education organizations within the framework of the Priority 2030 program and SECs. The share of the educational block in 2021–2023 accounts for 66.5% of the state program. Financing of directly scientific and scientific and technological activities is carried out according to the residual principle [ 7 ].
The process of creating scientific and educational centers (SECs) has not yet led to the formation of new scientific and educational consortiums capable of solving large-scale scientific problems. The educational agenda in them dominates over the scientific one. SECs do contribute to the involvement of scientists in the development of universities, but do not create conditions for the joint work of educational institutions with academic institutions as integral entities.
Prospects for the development of fundamental science until 2024 are largely determined by the implementation of the program of fundamental research and the participation of RAS institutes in the activities of the national project “Science and universities” through the activities of world-class scientific centers, centers for genomic and mathematical research, centers of the NTI competencies, programs for the creation of research facilities of the megascience class. The development of the system of grants from science foundations has given the support of basic science an important flexibility and individuality. At the same time, the loss of scientific status by the Academy of Sciences and the lack of coordination of its actions with the Russian Science Foundation, after its actual merger with the Russian Foundation for Basic Research, further increases disunity in the scientific community and its management system [ 8 ].
The attempts made to build an integral system from fundamental research through exploratory scientific and technological work to applied innovative developments, or an innovative lift, have not yet been successful. An example is the initiative of development, which is almost four years old, of complex scientific and technological programs of the full innovation cycle (CSTP), which provided for large-scale world-class scientific and technological projects, including in such important areas as new substances and materials, specialized robotics, baby food. For four years there has been discussion and adjustment, but not a single program has been launched. According to the idea, the state planned to provide support for exploratory R&D, and business was supposed to finance applied research and bring innovative products to the market, which ensured the unity of fundamental and applied science. So far, there is progress only in terms of business financing, in particular through Rosatom, but without state support. After the reformatting of the national project “Science” into “Science and Universities” in 2020, the development of CSTP actually became a nonpriority. In the approved SP STD, the planned financing of CSTP was reduced to two billion rubles per year (10 times less than the original passport of the national project “Science”), which does not allow us to consider even the already approved CSTP as powerful driver programs for the full scientific and technological cycle.
Currently, along with projects in industry state programs, a really significant state tool for the development of new scientific and technological areas in terms of applied and corporate science are the roadmaps of state companies launched in 2019 for the development of a number of high-tech areas, as well as “beacon projects” approved by the Government as part of strategic initiatives in 2021 as a continuation of the National Technology Initiative (NTI). It is assumed that the “beacon projects” of technology development should have a high multiplier effect for the development of the economy. In our opinion, beacon projects are more likely to be targeted innovative projects and do not have a large macroeconomic effect in the medium term, with the exception of the electric propulsion project. Moreover, they do not create a need for in-depth fundamental and exploratory research, nor do they entail any significant increase in country R&D expenses. These projects are, in essence, a continuation of the priorities adopted at the launch of the National Technology Initiative, a kind of NTI 2.0 [ 9 ].
To a large extent, there is no synergy of beacon projects with research and projects carried out within the framework of the roadmaps of state-owned companies and the activities of the SP STD, except for the areas of ICT and artificial intelligence technologies.
In the world practice of managing and supporting new areas of scientific and technological development by the state, the emphasis is on numerous research programs and partnerships created specifically to organize and support research in the field of new technologies, targeted funding is also provided through grant funds.
For example, in the field of quantum technologies at the EU level, the Quantum Flagship program (2018–2027) [ 10 ] is operating, and Germany is implementing the National Quantum Program (2021–2028). In the United States, in the field of new technologies in the electric power industry, there is the DOE Grid Modernization Initiative, a large program for the modernization of the US electric networks, which involves 17 national Laboratories operating under the auspices of the US Department of Energy [ 11 ].
These are quite long-term programs, while in Russia budget financing of roadmaps and programs is provided only until 2024. In particular, in the program “Digital economy of the Russian Federation”: for the development of quantum computing (13.3 billion rubles), artificial intelligence (24.6 billion rubles), 5G mobile communication networks (21.463 billion rubles), quantum communications (10.2 billion rubles). All together, these roadmaps cost about 1 billion dollars. State support abroad for similar areas is much larger: in the direction of quantum computing, in the United States—1.2 billion dollars, programs of the EU and individual European countries–a total of more than 5 billion euros, India—1.12 billion dollars; in the direction of artificial intelligence, China— 8 billion dollars, the United States — 6 billion dollars, programs of the EU and individual European countries—a total of more than 7 billion euros; in the direction of quantum communications, China—more than 15 billion dollars, Germany—more than 2 billion euros. At present, monitoring of the implementation of roadmaps by the state is entrusted to the Ministry of Economic Development of Russia.
The overall structure of science expenses in Russia is close to the similar structure in foreign countries. However, as is known, it is the sphere of applied research and development that is the most financially and capital intensive, while in Russian conditions it is here that the main deficit of investments and equipment is concentrated ( Table 8 ) [ 12 ].
Structure of internal current research and development expenses by type of work in 2020, %
Country | Fundamental research | Applied research | Development |
---|---|---|---|
USA | 16.4 | 19.0 | 64.5 |
China | 6.0 | 11.3 | 82.7 |
Japan | 13.0 | 19.4 | 67.6 |
Republic of Korea | 14.7 | 22.5 | 62.8 |
France | 22.7 | 41.4 | 36.0 |
Great Britain | 18.3 | 42.1 | 39.7 |
Russia | 18.8 | 20.0 | 61.2 |
Israel | 10.0 | 10.1 | 79.9 |
Czech Republic | 26.2 | 41.1 | 32.3 |
Source: OECD, Rosstat.
At present, the weakest link in the structure of the Russian scientific and technological complex is the link that ensures the transition from the stage of research and laboratory samples to pilot plants and small-scale production (TRL 4-7), 10 refining and scaling new technologies.
The main potential of applied and engineering research in Russia is concentrated in the system of state research centers of the Russian Federation and in the field of corporate science, concentrated mainly in the largest state corporations and companies with state participation.
The system of the public sector of applied science is the most important component of the national innovation system and unites 44 scientific organizations with the status of state scientific centers, the activities of which are aimed at creating and developing technologies, promoting the results of search, applied research and experimental development, including their own production of high-tech goods.
Today, the system of state research centers of the Russian Federation in terms of its functionality and variety of work performed is comparable to the world’s largest associations that carry out applied problem-oriented research and development, such as the Fraunhofer Society (Germany) and the network of Carnot Institutes (France).
The fundamental difference between the state research centers of the Russian Federation and academic and university science is the predominance of expenses on applied research and experimental development. Despite the fact that all state research centers of the Russian Federation are only 1% of the country’s organizations performing research and development, they account for 20% of the country’s expenses for applied research as part of DRDE. At the same time, the share of state research centers of the Russian Federation in DRDE across the country in 2020 reached 7.7% (91.1 billion rubles). At the same time, the share of R&D expenses in the DRDE structure at the expense of nonbudgetary sources in the system of state research centers of the Russian Federation exceeds 50%.
At the present stage, the problem of further development of the system of state research centers of the Russian Federation, as well as of all applied science in the Russian Federation, is, among other things, insufficient legal support for such activities. It is advisable to update the normative and managerial categories “applied scientific research,” “exploratory scientific research,” “experimental developments,” “scientific and technological groundwork,” to consolidate the concept “innovative projects of a full life cycle.” Groundbreaking work does not fit into the procurement system according to Federal Law No. 44-FZ of April 5, 2013, On the Contract System in the Field of Procurement of Goods, Works, Services to Meet State and Municipal Needs, and Federal Law No. 223 of July 18, 2011-FZ, On the Procurement of Goods, Works, Services by Certain Types of Legal Entities, and they need a special management system and their own special regulatory framework [ 13 ].
Despite the significant potential, the state’s attention to the development of the system of state research centers of the Russian Federation is almost absent. It should also be noted that the functions of managing applied research are not provided for in the regulations of any federal executive body. As a result, today hardly anyone is directly responsible for supporting applied science in the country.
It is advisable to create a special section (target item of expenses): “Research and development carried out by state research centers of the Russian Federation,” which implies targeted budgetary financing of research and development carried out by the state research centers of the Russian Federation according to agreed development programs, including for organizations that have an organizational and legal form of commercial organization.
The status of state research centers should be clarified, both taking into account the American experience of “national laboratories” and the experience of the Kurchatov Institute and the Zhukovsky Center for Scientific Research, for which special legal acts were adopted.
It should be noted that more than 40% of the total national funding for the physical and technological sciences is concentrated in the system of US national laboratories, while federal funding accounts for up to 70% of all R&D expenditures, primarily for the operation of unique scientific facilities used by universities and industry. Many national laboratories operate in a government-owned, contractor-operated format, a model that enables breakthrough research in promising areas based on the use of large state-funded scientific facilities and equipment and the private initiative of the contractor. At the same time, network interactions formed for specific tasks allow national laboratories to solve interdisciplinary problems in a wide range of areas [ 14 ].
In general, the formation of intersectoral, interdisciplinary national research centers of applied science on the basis of the leading state research centers of the Russian Federation and the scientific research centers, following the example of the Kurchatov Institute and the Zhukovsky Center for Scientific Research, will allow planning and implementing complex scientific and technological projects and full-cycle programs that meet the challenges and priorities of the Strategy for Scientific and Technological Development of the Russian Federation.
The system of innovation development institutions that has developed in Russia is mainly focused on a variety of startup support mechanisms: the Innovation Promotion Fund, the Skolkovo Foundation, Rosnano, NTI, RVC, etc. The activities of development institutions, for all their importance for the development of innovations, are characterized by limited scientific, especially the fundamental, component. Domestic startups in the overwhelming majority do not develop, but use technologies of varying degrees of readiness for the commercialization of products based on them. The few exceptions are the most successful projects of Rosnano (for example, the company Oscial in the field of nanotubes). The bottleneck in the scientific and innovation cycle is the stage of pilot development and scaling, which in the current system of development institutions can be mainly handled by Rosnano only (to a lesser extent, by FRP and FPI). Currently, VEB.RF is in charge of coordinating development institutions, and a new model of interaction (“seamless integration”) and the so-called “innovation lift” still needs to be developed.
Applied science in Russia is concentrated mainly both in state research centers and in the largest state corporations and companies with state participation, which are obliged to implement innovative development programs (IDP) since 2011 [ 15 ] ( Table 9 ). At present, the list of state-owned companies implementing IDP includes 57 state corporations, joint-stock companies and federal state unitary enterprises. In 2020, the total expenses of state-owned companies for the implementation of IDP amounted to about 1.4 trillion rubles, total R&D expenses 552 billion rubles. At the same time, state-owned companies’ R&D expenses reached 232 billion rubles, which is more than 60% of applied science expenses for the Russian Federation as a whole.
R&D expenses of the largest state-owned companies by industry
Sectors of the economy | R&D spending | 2017 | 2018 | 2019 | 2020 |
---|---|---|---|---|---|
Space sector | pace | 104.2 | 92.8 | 235.5 | |
% of revenue | 54.3 | 61.9 | 57.6 | 51.5 | |
Aircraft industry | pace | 92.0 | 146.7 | 67.0 | |
% of revenue | 10.0 | 10.2 | 18.6 | 10.2 | |
Shipbuilding, automated control systems and marine engineering | pace | 78.9 | 86.7 | 94.9 | |
% of revenue | 13.4 | 10.4 | 8.2 | 7.3 | |
Chemistry and pharmaceuticals | pace | 86.5 | 67.0 | 94.9 | |
% of revenue | 22.7 | 18.3 | 28.8 | 23.2 | |
Extraction and processing of raw materials | pace | 109.5 | 106.5 | 91.7 | |
% of revenue | 0.2 | 0.2 | 0.3 | 0.3 | |
Energy | pace | 108.1 | 124.7 | 167.5 | |
% of revenue | 0.5 | 0.6 | 0.6 | 1.1 | |
Transport and infrastructure | pace | 199.3 | 109.7 | 95.7 | |
% of revenue | 0.3 | 0.7 | 0.7 | 0.7 | |
Communications and telecommunications | pace | 150.4 | 143.4 | 102.8 | |
% of revenue | 1.2 | 1.1 | 1.5 | 1.4 |
Source: Ministry of Economic Development of Russia, ANO VEB Institute.
The range of technologies developed by state-owned companies is very wide, and, as can be seen from Fig. 2 , in a number of traditional areas in general, according to the companies themselves, it is not inferior to the level of development in the leading foreign peer companies. However, in terms of microelectronics technologies, space and energy technologies, there is a significant lag behind the world level.
Comparative level of technological development of state-owned companies. The size of the “bubble” corresponds to the number of technologies analyzed.
At the same time, state-owned companies note that there is a shortage of breakthrough promising research that cannot be overcome by corporate research centers and state research centers, and therefore special approaches and mechanisms are needed to support the formation of scientific and technological groundwork and breakthrough risky developments. At present, business mainly plans its activities in the short and medium term and is not ready to set fundamental tasks for scientists that require serious exploratory research.
Despite calls for an outpacing increase in private R&D funding, state-owned companies have not increased R&D expenses in recent years, and somewhere have lowered its relative (to revenue) level. 11 The state, through its representatives on the boards of directors, does not set them the task of increasing these expenses. In many ways, this is not just the result of inconsistency with the budget plans of corporations, but the lack of long-term sustainable priorities for technological and innovative development on the part of the state and companies.
At present, all FEED projects are financed in a general manner within the framework of investment programs of state-owned companies, and priority is usually given to low-risk projects with a high share of mastered imported technologies. In the new times that have come, the requirement to ensure technological sovereignty forces the creation of high-risk projects with a significant innovative and breakthrough component.
Attention to FEED in recent years has been pushed aside by the demand for the implementation of specific KPIs, mainly of a volumetric financial focus. It is advisable not to abolish, but to reformat the innovative development programs of state-owned companies (FEED 2.0) and their financing mechanisms, not excluding their transformation into subprograms of long-term programs for the development of state corporations. The need for stimulation, and for “forcing innovation” has not yet disappeared. The following necessary institutional innovations can be identified:
— Highlighting, as part of innovative development programs (DPR subprograms), of activities that are part of the roadmaps for the implementation of agreements between companies and the state on the development of advanced technologies; combining innovative programs with corporate digitalization programs and programs to reduce greenhouse gas emissions in order to avoid the multiplication of organizational structures within companies and the dispersion of efforts following every trendy agenda.
— Providing public-corporate innovators with the right to take risks when conducting research in the early stages and transition to managing a portfolio of innovative projects instead of waiting for the economic efficiency of each project.
— Initiating the creation of new ways for financing innovative projects at the stages of R&D and development through specialized corporate innovation support programs and corporate venture funds, or industry-specific R&D funds with a deduction of 1.5% of profits under the current legislation.
— Encouraging corporate science to start research in breakthrough technological areas (for a 10–15 year perspective), which require fundamental/exploratory work to be carried out jointly with external partners.
Thus, based on the results of the comparison of the level and trends in the development of the scientific and technological sphere in Russia with the leading foreign countries, carried out in this article, we can conclude that there is a potential in the field of fundamental science and high-tech big business that is sufficient to maintain technological parity. At the same time, for a technological breakthrough with the aim of Russia’s entry into the top five countries—world technological leaders—it is necessary to solve a set of problems related to the multiplicity of scientific and technological priorities, restrictions on the financing of science and the inconsistency of policy in relation to state programs of scientific and technological development, as well as insufficient support for the applied and corporate science sector.
In this regard, in the second part of the article, a set of measures will be proposed to accelerate scientific and technological development, including taking into account the need to level significant restrictions in which the domestic science sector found itself in conditions of technological blockade.
The authors declare that they have no conflicts of interest.
1 Decree of the President of the Russian Federation No. 204 of May 7, 2018, On the National Goals and Strategic Objectives of the Development of the Russian Federation for the Period until 2024; Decree of the President of the Russian Federation No. 474 of July 21, 2020, On the National Development Goals of the Russian Federation for the Period until 2030.
2 Concept of Long-Term Socio-Economic Development of the Russian Federation for the period until 2020, approved by the Order of the Government of the Russian Federation No. 1662-r of November 17, 2008.
3 According to the materials of Institute for Statistical Studies and Economics of Knowledge, Higher School of Economics. https://issek.hse.ru/news/482453668.html . Cited June 5, 2022.
4 Source: Federal Office of Statistics of Germany, Bureau of Statistics of the Czech Republic.
5 A. M. Sergeev, How can we do science under sanctions? https://rg.ru/2022/05/31/1-iiunia-sostoiatsia-vybory-novyh-chlenov-rossijskoj-akademii-nauk.html . Cited June 5, 2022.
6 The assessment is based on a modified methodology of the Russian Ministry of Education and Science for calculating the indicator “Place of the Russian Federation in terms of research and development, including through the creation of an effective system of higher education.” PRF = (PRFOESD in terms of the number of researchers in full-time equivalent among the world’s leading countries × 0.3) + (PRFDRDE in terms of research and development expenses × 0.3) + (PRF A in terms of share in the total number of articles indexed in international databases data × 0.15) + (PRF P in terms of share in the total number of patent applications × 0.2) + PRF TOP500 in terms of the presence of top 500 universities in the QS ranking × 0.05). The indicator is expressed in whole units, and the weight coefficients are based on an assessment of the impact of the components of the statistical indicator on the development of the scientific and technological complex of the Russian Federation. The data are divided into main areas: resource potential (based on the indicators of staffing and the state’s financial expenses on research and development), the effectiveness of scientific activity (based on indicators of publication and patent activity), as well as the effectiveness of the higher education system based on the position of Russian universities in the international QS ranking.
7 Program of fundamental scientific research in the Russian Federation for the long term (2021–2030), approved by the Order of the Government of the Russian Federation No. 3684-r of December 31, 2020.
8 State Program “Scientific and technological development of the Russian Federation,” approved by the Decree of the Government of the Russian Federation of March 29, 2019 No. 377 (as amended by the Decree of the Government of the Russian Federation No. 1814of October 22, 2021).
9 A. M. Sergeev, How can we do science under sanctions? https://rg.ru/2022/05/31/1-iiunia-sostoiatsia-vybory-novyh-chlenov-rossijskoj-akademii-nauk.html . Cited June 5, 2022; A. N. Klepach, Socio-technological challenges of the Russian economy, Moscow Economic Forum MAEF. https://cyberleninka.ru/article/n/sotsialnyei-tehnologicheskie-vyzovy-rossiyskoy-ekonomiki/viewer . Cited June 5, 2022.
10 TRL. There are nine levels of technology readiness. From the first to the sixth levels, this is the development of technologies, which is carried out within the framework of research and development. From the seventh level and above, development engineering begins, or a demonstration of the operability of technologies on real devices under development. TRL 1—approval and publication of the basic principles of technology, TRL 2—formulation of the concept of technology and evaluation of the scope, TRL 3—beginning of research and development. Validation of characteristics, TRL 4—verification of the main technological components in the laboratory, TRL 5—verification of the main technological components in real conditions, TRL 6— testing a model or prototype in real conditions, TRL 7—demonstration of a prototype (trial model) in operation, TRL 8—completion of development and testing of the system in operation, TRL 9—demonstration of the technology in its final form during flight tests of the sample
11 FEED is a comprehensive tool for the development of innovations in companies, their structure includes activities in the following areas: development and implementation of innovative projects, improvement of innovation management mechanisms in companies, including in the field of intellectual property, development of an ecosystem of “open innovations” through interaction with small and medium-sized companies, organizations of science, higher education and objects of innovation infrastructure (innovation clusters and technology platforms), development of mechanisms for financing and investment in the innovation sector (including venture funds).
Translated by S. Avodkova
Big ideas and raw materials, and turn them into unique devices, which are integrated into the global high-tech supply chain, our engineers take, our collaboration with scientists, builds on a deep foundation of engineering know-how. we delve into every detail and nuance to meet the challenge of developing and scaling knowledge-intensive devices., passionate, up-and-coming engineers, we value determined, self-driven employees, and help each of them find the right path forward for dynamic growth., optical scientists.
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Scientists raise a rosette loaded with water samples to measure carbon dioxide in the ocean. (Image credit: Nicolas Gruber/ ETH Zurich.)
Today, NOAA and the U.S. Department of Energy (DOE) signed a memorandum of agreement (MOA) on future collaborations regarding marine carbon dioxide removal research and development. As a climate solution, marine carbon dioxide removal is an important pathway to achieve the broader Biden Administration goal for the U.S. to reach net-zero emissions of greenhouse gases by 2050.
This MOA will formalize collaboration between NOAA and DOE to share expertise on research and technology development, as well as avoid duplicative work. The MOA makes clear that combining the ocean science expertise of NOAA with the carbon dioxide removal and energy science and technology expertise of DOE will be a powerful way to advance the state of marine carbon dioxide removal science and strengthen the existing relationship between both agencies.
“The science is clear,” said NOAA Administrator Rick Spinrad, Ph.D. “In order to limit global warming to 1.5C or even 2C, we not only have to bring our emissions of greenhouse gases to net-zero rapidly, but we also must remove carbon dioxide from the atmosphere. This MOA, utilizing the great strengths of NOAA and DOE, means we can develop the marine carbon dioxide removal research and technology necessary to tackle the climate crisis.”
“Carbon dioxide removal methods have the potential to mitigate and remove hundreds of millions of tons of harmful carbon dioxide emissions per year,” said DOE Under Secretary for Science and Innovation Dr. Geri Richmond. “DOE is excited to partner with NOAA under this MOA to advance our collaborative research and development efforts in this growing area of marine carbon dioxide removal and slow the harmful effects of climate change.”
The ocean can play a vital role as a solution to human-caused climate change. It naturally absorbs approximately one third of human-emitted carbon dioxide from the atmosphere, and it has the potential to hold over 17 times more carbon than soils and land combined. Enhancing the uptake of carbon dioxide into the ocean through marine carbon dioxide removal via a variety of biological, chemical and engineered methods offers great potential for helping maintain a livable climate and may address existing ocean problems such as surface ocean acidification.
Under the MOA, NOAA and DOE recognize four responsibilities: (1) coordination and collaboration, (2) acceleration of research and development infrastructure, including facilities, data management and feasibility studies, (3) development of protocols for accountable and science-based marine carbon dioxide removal for ecosystem safety, social benefit and economic viability, and (4) the potential for future additional collaboration between both agencies.
The agreement will be the first formalized interagency partnership on marine carbon dioxide removal, which will strengthen existing United States government coordination efforts through the National Science Technology Council’s Marine Carbon Dioxide Removal Fast Track Action Committee.
Read the full memorandum of agreement at NOAA's FOIA Reading Room website .
Media contact
Tom Di Liberto, Tom.DiLiberto@noaa.gov , (202) 993-0024
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Penn State is currently seeking a top frontline fundraiser in the role of Assistant/Associate Director of Development to engage alumni and friends as partners in supporting the College of Engineering, one of the nation’s leading educators of world-class engineers and leading producers of world-class research. As a member of the Division of Development and Alumni Relations (DDAR), you can play an integral role in Penn State’s future and contribute to one of the most successful fundraising and alumni relations operations in the country.
The University is committed to ensuring that diversity, equity, inclusion, and belonging are central to the success of a world-class research institution. We are dedicated to fostering institutional change required to realize a more socially just University and we value inclusion as a core strength and an essential element of our public service mission. We are concerned uniquely with the institutional change required for visioning and realizing a more socially just University: equity.psu.edu/diversity-resources . The University’s commitment to diversity, equity, inclusion, and belonging is mirrored in the Division of Development and Alumni Relations’ own ongoing work in these spaces: raise.psu.edu/diversity-equity-and-inclusion
Reporting to the Senior Director of Development and Alumni Relations and working closely with the college’s leadership, as well as other partners and central development offices, this Assistant/Associate Director of Development will:
This position will be filled as Professional or Intermediate Professional depending upon the successful candidate’s competencies, education, and experience. It typically requires a bachelor’s degree or higher plus one year of related experience for Professional. Additional experience and/or education and competencies are required for higher level jobs. The successful candidate will also have:
Operation of a motor vehicle as part of the position’s duties and a valid driver’s license are required. Successful completion of a motor vehicle records check, in addition to standard background checks, is also required.
DDAR is supportive of flexible work arrangements when aligned with the ability to meet the needs of the unit and the essential duties of the position. Questions related to flexible work arrangements should be directed to the hiring manager during the interview process.
The College of Engineering Philanthropy will have a special impact in the College of Engineering, whose more than 95,000 living alumni include leaders, innovators, and entrepreneurs in every field of engineering. Its undergraduate program is the second-largest in the country, and, along with the Engineering graduate program, it is ranked among the top twenty-five of its kind nationwide by U.S. News and World Report. Across twelve departments and schools and more than thirty research centers, the College of Engineering’s world-class faculty is in the top ten for number of grants and publications, and it is committed to interdisciplinary research and hands-on education that prepares students for success in a rapidly changing world: engr.psu.edu
Penn State’s Division of Development and Alumni Relations If you believe in the power of higher education—and philanthropy—to shape the public good, you’ll excel right here in Penn State’s Division of Development and Alumni Relations (DDAR). Our organization includes more than 500 professionals engaging a community of more than 700,000 alumni who believe in the power of giving back. Across our interdisciplinary teams of fundraisers, alumni relations professionals, communicators, event planners, financial experts, and more, there is a place for you to make a difference in the lives of students and faculty while taking your own career to new heights. Learn more about us at raise.psu.edu and explore the success of our most recent campaign at greaterpennstate.psu.edu .
Building a Career and a Life at Penn State Across twenty-four campuses and an online World Campus, our 100,000 students and 17,000 faculty and staff know the real measure of success goes beyond the classroom—it’s the positive impact made on communities across the globe. Penn State consistently ranks among the top academic and research universities in the world: psu.edu/this-is-penn-state/facts-and-rankings
Penn State is a diverse and exciting institution that embraces individual uniqueness, fosters a culture of inclusion that supports both broad and specific diversity initiatives, leverages the educational and institutional benefits of diversity in society and nature, and engages all individuals to help them thrive: equity.psu.edu
This position is based at the University Park campus, located in State College, Pennsylvania. State College is ranked among the lowest-stress and safest small cities in the country, with excellent public schools, beautiful parks and other natural assets, and a broad range of cultural and athletic events and venues: statecollegepa.us and statecollege.com
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Treatment holds promise for painlessly targeting affected areas without weakening immune system
BWH Communications
Researchers have developed a novel treatment to reverse hair loss caused by the autoimmune disease alopecia areata, using a microneedle patch to painlessly target affected areas of the skin.
Alopecia areata causes hair loss when T cells mistakenly attack follicles. To restore control over hyperactive immune cells, researchers from Brigham and Women’s Hospital and MIT delivered T cell regulators directly to sites of hair loss to halt autoimmune activity. Findings, published in Advanced Materials , demonstrated marked and lasting increases in hair regrowth in mice models of the disease.
Our immune system evolved to safeguard against the overactivation that occurs in autoimmune conditions. In alopecia areata, the specialized cells known as Regulatory T cells (T-regs) fall short in protecting hair follicles. Current immunosuppressants used to treat alopecia areata target both T cells and T-regs, failing to address the core issue and increasing the risk of disease recurrence once treatment stops. By suppressing the entire immune system, they leave patients vulnerable to infections.
Rather than globally suppressing the immune system, the approach tested in this study locally restores immune activity directly at sites of hair loss by increasing levels of T-regs. This targeted approach was achieved with a microneedle patch, which delivers drugs across the tough outer layer of skin more effectively than topical creams and avoids stimulation of pain receptors located deeper within the skin.
“Our strategy tackles two major challenges in treating autoimmune skin diseases,” said co-corresponding author Natalie Artzi of the Brigham’s Engineering in Medicine Division in the Department of Medicine. “Our patches enable local delivery of biologics, which, instead of suppressing the immune system, promote regulatory T cells in the skin. This restores immune balance and resolves the T cell attack on hair follicles, offering a potential long-term solution without compromising the immune system’s ability to defend against infections and malignancies.”
“When it comes to autoimmune-mediated skin diseases, where we have direct access to the skin, we must surpass the use of systemic immunosuppressants that shut down the entire immune system,” said co-corresponding author Jamil Azzi , an immunologist in the Brigham’s Renal Division in the Department of Medicine. “While topical therapy often fails to penetrate the skin’s outer layer, our patches improve the local delivery of biologics to the deeper layers of diseased skin and reprogram the immune system to generate tolerance at the site of antigen encounter.”
“Our strategy tackles two major challenges in treating autoimmune skin diseases.” Natalie Artzi
The researchers, including co-first authors Nour Younis and Núria Puigmal, both of Brigham’s Department of Medicine, observed with RNA sequencing that in alopecia tissues, there were changes in the STAT-5/Interleukin-2 (IL-2), a signaling pathway that promotes T-reg proliferation. IL-2 and CCL22, which the researchers had previously shown attract and expand the presence of T-regs in a specific area, were loaded into the microneedle patch. The patches were applied to mice models of alopecia 10 times over a course of three weeks, with more than eight weeks of observation. Hair regrowth was observed as early as three weeks after the initiation of treatment. The researchers also tested microneedle patches loaded with baricitinib, a drug approved for severe alopecia areata, but found that T-reg recruitment was inferior to that associated with the IL-2/CCL22 patch.
The microneedle patch also was found to have good shelf-life stability, improving prospects of its clinical translation. While the therapy is not ready for clinical use, the researchers are pursuing further development and testing. Additionally, they are exploring the possibility of applying their approach to other immune-mediated skin diseases, such as vitiligo and psoriasis.
“Microneedles offer a promising avenue for targeted and localized delivery of therapeutics to the skin,” said Artzi. “Their ability to precisely administer drugs directly to the affected area of the skin enables more effective modulation of the immune response while minimizing systemic side effects. This targeted approach holds great potential for improving treatment outcomes and reducing the burden of autoimmune and immune-mediated diseases on patients’ lives.”
Other co-authors from Brigham include Andrew Badaoui, Dongliang Zhang, Claudia Morales, Anis Saad, Diane Cruz, Nadim Al Rahy, Andrea Daccache, Triana Huerta, Christa Deban, Ahmad Halawi, John Choi, Pere Dosta, Christine Lian, and Abdallah El Kurdi.
Funding: The Department of Medicine at Brigham and Women’s Hospital supported this work through the Ignite Fund Award and the Shark Tank Fund Award.
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Climate change is the greatest threat to health and wellbeing facing the world in the 21st century. The climate crisis is estimated to push 132 million people into extreme poverty by 2030—one-third of these will be driven by the impacts of climate change on health alone. Despite the outsized impact, current investments in the nexus of climate change and health are extremely low.
To increase and prioritize investments at the scale needed to sustainably finance climate and health action, we need partnerships across institutional and sectoral boundaries to identify the most impactful and cost-effective solutions.
The Development Bank Working Group for Climate-Health Finance, established in July 2023, comprises Multilateral Development Banks (MDB) and Public Development Banks (PDBs). The goal of the group is to enhance its collective impact by supporting countries to respond to the health impacts of climate change and elevating the health sector's role in climate change adaptation and mitigation.
This event will introduce the new Roadmap for Climate-Health Finance and Action of the Development Bank Working Group. The roadmap outlines a common, strategic approach to urgently raise, prioritize, and drive climate and health commitments to finance a people-centered approach for climate and health action. The event will answer these questions:
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For the first time, eleven Multilateral and Public Development Banks have come together to optimize their efforts and maximize investments in climate and health. Together, the group has developed the Joint Roadmap for Climate-Health Finance and Action (PDF) , which outlines a common strategy to urgently increase and prioritize investments responding to the health impacts brought about by climate change.
With a focus on strong partnerships with governments, civil society, the private sector, and other stakeholders to tailor investments to specific country needs, the roadmap outlines six areas to guide this collective approach:
Report: Roadmap for Climate-Health Finance and Action (PDF)
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Question What is the association between melatonin use and the development and progression of age-related macular degeneration (AMD)?
Findings In this cohort study of 121 523 patients with no history of AMD aged 50 years or older, taking melatonin was associated with a decreased risk of developing AMD. Likewise, among 66 253 patients with preexisting nonexudative AMD, melatonin supplementation was negatively associated with the rate of progression to exudative AMD.
Meaning These findings provide a rationale for expanding clinical research on the potential therapeutic efficacy of melatonin in preventing AMD development or its progression.
Importance Melatonin has been shown to oppose several processes that are known to mediate age-related macular degeneration (AMD), but whether melatonin can confer benefits against AMD remains unclear.
Objective To examine the association between melatonin supplementation and the risk of the development or progression of AMD.
Design, Setting, and Participants This retrospective cohort study accessed data from TriNetX, a national database of deidentified electronic medical records from both inpatient and outpatient health care organizations across the US, between December 4, 2023, and March 19, 2024. Patients aged 50 years or older, 60 years or older, and 70 years or older with no history of AMD (AMD-naive group) and with a history of nonexudative AMD (nonexudative AMD group) were queried for instances of melatonin medication codes between November 14, 2008, and November 14, 2023. Patients were then classified into either a melatonin group or a control group based on the presence of medication codes for melatonin. Propensity score matching (PSM) was performed to match the cohorts based on demographic variables, comorbidities, and nonmelatonin hypnotic medication use.
Exposure The presence of at least 4 instances of melatonin records that each occurred at least 3 months apart.
Main Outcomes and Measures After PSM, the melatonin and the control cohorts were compared to evaluate the risk ratios (RRs) and the 95% CIs of having an outcome. For the AMD-naive group, the outcome was defined as a new diagnosis of any AMD, whereas for the nonexudative AMD group, the outcome was progression to exudative AMD.
Results Among 121 523 patients in the melatonin-naive group aged 50 years or older (4848 in the melatonin cohort [4580 after PSM; mean (SD) age, 68.24 (11.47) years; 2588 female (56.5%)] and 116 675 in the control cohort [4580 after PSM; mean (SD) age, 68.17 (10.63) years; 2681 female (58.5%)]), melatonin use was associated with a reduced risk of developing AMD (RR, 0.42; 95% CI, 0.28-0.62). Among 66 253 patients aged 50 years or older in the nonexudative AMD group (4350 in the melatonin cohort [4064 after PSM; mean (SD) age, 80.21 (8.78) years; 2482 female (61.1%)] and 61 903 in the control cohort [4064 patients after PSM; mean (SD) age, 80.31 (8.03) years; 2531 female (62.3%)]), melatonin was associated with a reduced risk of AMD progression to exudative AMD (RR, 0.44; 95% CI, 0.34-0.56). The results were consistent among subsets of individuals aged 60 years or older (AMD-naive cohort: RR, 0.36 [95% CI, 0.25-0.54]; nonexudative AMD cohort: RR, 0.38 [95% CI, 0.30-0.49]) and 70 years or older (AMD-naive cohort: RR, 0.35 [95% CI, 0.23-0.53]; nonexudative AMD cohort: RR, 0.40 [95% CI, 0.31-0.51]).
Conclusions and Relevance Melatonin use was associated with a decreased risk of development and progression of AMD. Although lifestyle factors may have influenced this association, these findings provide a rationale for further research on the efficacy of using melatonin as a preventive therapy against AMD.
Jeong H , Shaia JK , Markle JC , Talcott KE , Singh RP. Melatonin and Risk of Age-Related Macular Degeneration. JAMA Ophthalmol. Published online June 06, 2024. doi:10.1001/jamaophthalmol.2024.1822
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June 7, 2024
No parent wants to see their baby sick. But a child's first exposure to influenza is actually very important—it can impact their natural protection against future flu viruses.
Now, Gordon, a professor of epidemiology and global public health at Michigan Public Health, has been awarded a $6.7 million five-year grant to advance her innovative research into influenza immunity development among children. Flu Lab , an organization that supports efforts to advance innovative solutions to persistent problems in the prevention and treatment of influenza, has funded the grant for Gordon's FluGuardians: Michigan Influenza Immunity Cohort through the end of 2028.
"This study represents a monumental step toward understanding how early influenza exposure—whether through infection or vaccination—shapes the immune systems of children in the long term," said Gordon, who is also principal investigator at the University of Michigan Biosciences Initiative's Michigan Center for Infectious Disease Threats. "We're immensely grateful to Flu Lab for supporting research that has the potential to transform our approach to influenza prevention and immunity."
University of Michigan's Research Foundations Partnerships Office , launched in 2023, played a critical role in helping to secure funding for this project.
Gordon and her research team will focus on the comprehensive study of flu immunity development, from infancy through childhood. The ambitious project aims to enroll up to 850 infants in Ann Arbor within six weeks of birth, with the goal of closely following their immune responses to both influenza infection and vaccination.
The FluGuardians study is leveraging a Michigan Medicine-led food allergy cohort study, the Michigan Sibling Immunity Birth Study, which is also enrolling participants this year. With 680 to 765 healthy children anticipated to participate in both studies, the research will not only investigate natural infection and vaccine-imprinted immune responses but also examine the broader immunological landscape, including innate immunity.
The study's techniques include standard serological testing, systems serology using Luminex technology, and advanced machine learning methods to analyze the complex data. Supplementing Gordon's established Dissection of Influenza Vaccination and Infection for Childhood Immunity Consortium study—conducted in partnership with St. Jude Children's Research Hospital—the research will explore how initial exposures shape B and T cell responses, potentially leading to recommendations for tailoring immunizations in children.
"The community in Ann Arbor, known for its high infant influenza vaccination rates and enthusiastic participation in research studies, offers a prime setting for this cohort study," Gordon said. "Our connection with the local population, combined with their consistent engagement, provides a unique opportunity to address important questions about influenza immunity."
The findings from the study are expected to not only contribute significantly to the field of influenza research but also to inform strategies for the development and evaluation of next-generation and universal flu vaccines.
The very first flu virus you encounter can have a long-lasting influence on how your immune system responds to flu viruses in the future. Through a process called imprinting, our bodies create antibodies the first time we get the flu, and researchers have found that these antibodies stick with us for the rest of our lives. "Every time we encounter a flu virus with similarities, our immune system tends to rely on past responses rather than creating a new one," Gordon said. "While this can sometimes be effective, other times it can lead to a less optimal response, making it harder to fight off new strains. For example, due to imprinting, your immune system might use old tactics to fight off a virus, which might not be perfectly suited to fighting the new virus."
In addition, there is some evidence that this first exposure to the flu may protect you against severe infection from novel flu viruses, like H5N1, in the event of a pandemic. But how this occurs is not known.
Contact Andrea LaFerle Director of Public Relations and Marketing University of Michigan School of Public Health [email protected] 734-764-8094
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R&D is the series of activities that companies undertake to innovate and introduce new products and services or to improve their existing offerings. Learn about the different types of R&D, the advantages and disadvantages, and the accounting treatment for R&D costs.
Research and development ( R&D or R+D; also known in Europe as research and technological development or RTD) [1] is the set of innovative activities undertaken by corporations or governments in developing new services or products, and improving existing ones. [2] [3] Research and development constitutes the first stage of development of a ...
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The National Organization of Research Development Professionals (NORDP) defines the goal of Research Development offices as supporting the efforts of faculty to secure extramural research funding and initiate and nurture critical partnerships throughout the institutional research enterprise, among institutions, and with external stakeholders.
Reach out to the Office of Research and Economic Development by email or by phone at 208-885-6689 today. Office of Research & Economic Development. Physical Address: Morrill Hall 105. Mailing Address: 875 Perimeter Drive MS 3010 University of Idaho Moscow, ID 83844-3010. Phone: 208-885-5663.
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Importance Melatonin has been shown to oppose several processes that are known to mediate age-related macular degeneration (AMD), but whether melatonin can confer benefits against AMD remains unclear.. Objective To examine the association between melatonin supplementation and the risk of the development or progression of AMD.. Design, Setting, and Participants This retrospective cohort study ...
University of Michigan's Research Foundations Partnerships Office, launched in 2023, played a critical role in helping to secure funding for this project. Gordon and her research team will focus on the comprehensive study of flu immunity development, from infancy through childhood.